Pre-Exposure to Ionizing Radiation Stimulates DNA Double Strand Break End Resection, Promoting the Use of Homologous Recombination Repair

The choice of DNA double strand break (DSB) repair pathway is determined at the stage of DSB end resection. Resection was proposed to control the balance between the two major DSB repair pathways, homologous recombination (HR) and non-homologous end joining (NHEJ). Here, we examined the regulation o...

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Udgivet i:PLoS One
Main Authors: Nakajima, Nakako Izumi, Hagiwara, Yoshihiko, Oike, Takahiro, Okayasu, Ryuichi, Murakami, Takeshi, Nakano, Takashi, Shibata, Atsushi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380452/
https://ncbi.nlm.nih.gov/pubmed/25826455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122582
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