Inhibition of the HDAC/Suv39/G9a pathway restores the expression of DNA damage-dependent major histocompatibility complex class I-related chain A and B in cancer cells

Immunotherapy is expected to be promising as a next generation cancer therapy. Immunoreceptors are often activated constitutively in cancer cells, however, such levels of ligand expression are not effectively recognized by the native immune system due to tumor microenvironmental adaptation. Studies...

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Publicado en:Oncol Rep
Autores principales: Nakajima, Nakako Izumi, Niimi, Atsuko, Isono, Mayu, Oike, Takahiro, Sato, Hiro, Nakano, Takashi, Shibata, Atsushi
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2017
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562072/
https://ncbi.nlm.nih.gov/pubmed/28677817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.5773
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