VE-821, an ATR inhibitor, causes radiosensitization in human tumor cells irradiated with high LET radiation

BACKGROUND: High linear energy transfer (LET) radiation such as carbon ion particles is successfully used for treatment of solid tumors. The reason why high LET radiation accomplishes greater tumor-killing than X-rays is still not completely understood. One factor would be the clustered or complex-t...

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Detalhes bibliográficos
Publicado no:Radiat Oncol
Main Authors: Fujisawa, Hiroshi, Nakajima, Nakako Izumi, Sunada, Shigeaki, Lee, Younghyun, Hirakawa, Hirokazu, Yajima, Hirohiko, Fujimori, Akira, Uesaka, Mitsuru, Okayasu, Ryuichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554350/
https://ncbi.nlm.nih.gov/pubmed/26286029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-015-0464-y
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