Hsp90 inhibitor is a good candidate for effective combination therapy with carbon ions

Eitemau Tebyg

• The combination of Hsp90 inhibitor 17AAG and heavy-ion irradiation provides effective tumor control in human lung cancer cells
  gan: Hirakawa, Hirokazu, et al.
  Cyhoeddwyd: (2015)
• The purine scaffold Hsp90 inhibitor PU-H71 sensitizes cancer cells to heavy ion radiation by inhibiting DNA repair by homologous recombination and non-homologous end joining
  gan: Lee, Younghyun, et al.
  Cyhoeddwyd: (2016)
• TAS-116, a novel Hsp90 inhibitor, selectively enhances radio-sensitivity of human cancer cells to X-rays and carbon ion radiation
  gan: Lee, Younghyun, et al.
  Cyhoeddwyd: (2016)
• Indirect action to cell killing by SOBP carbon-ion beams
  gan: Hirayama, Ryoichi, et al.
  Cyhoeddwyd: (2014)
• PU-H71, a novel Hsp90 inhibitor, as a potential cancer-specific sensitizer to carbon-ion beam therapy
  gan: Li, Huizi Keiko, et al.
  Cyhoeddwyd: (2016)