DNA Damage Response Proteins and Oxygen Modulate Prostaglandin E(2) Growth Factor Release in Response to Low and High LET Ionizing Radiation

Common cancer therapies employ chemicals or radiation that damage DNA. Cancer and normal cells respond to DNA damage by activating complex networks of DNA damage sensor, signal transducer, and effector proteins that arrest cell cycle progression, and repair damaged DNA. If damage is severe enough, t...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Allen, Christopher P., Tinganelli, Walter, Sharma, Neelam, Nie, Jingyi, Sicard, Cory, Natale, Francesco, King, Maurice, Keysar, Steven B., Jimeno, Antonio, Furusawa, Yoshiya, Okayasu, Ryuichi, Fujimori, Akira, Durante, Marco, Nickoloff, Jac A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670845/
https://ncbi.nlm.nih.gov/pubmed/26697402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00260
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