DNA Damage Response Proteins and Oxygen Modulate Prostaglandin E(2) Growth Factor Release in Response to Low and High LET Ionizing Radiation

Common cancer therapies employ chemicals or radiation that damage DNA. Cancer and normal cells respond to DNA damage by activating complex networks of DNA damage sensor, signal transducer, and effector proteins that arrest cell cycle progression, and repair damaged DNA. If damage is severe enough, t...

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Foilsithe in:Front Oncol
Main Authors: Allen, Christopher P., Tinganelli, Walter, Sharma, Neelam, Nie, Jingyi, Sicard, Cory, Natale, Francesco, King, Maurice, Keysar, Steven B., Jimeno, Antonio, Furusawa, Yoshiya, Okayasu, Ryuichi, Fujimori, Akira, Durante, Marco, Nickoloff, Jac A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2015
Ábhair:
Oncology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670845/
https://ncbi.nlm.nih.gov/pubmed/26697402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00260
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