DNA Damage Response Proteins and Oxygen Modulate Prostaglandin E(2) Growth Factor Release in Response to Low and High LET Ionizing Radiation

Common cancer therapies employ chemicals or radiation that damage DNA. Cancer and normal cells respond to DNA damage by activating complex networks of DNA damage sensor, signal transducer, and effector proteins that arrest cell cycle progression, and repair damaged DNA. If damage is severe enough, t...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Oncol
Auteurs principaux: Allen, Christopher P., Tinganelli, Walter, Sharma, Neelam, Nie, Jingyi, Sicard, Cory, Natale, Francesco, King, Maurice, Keysar, Steven B., Jimeno, Antonio, Furusawa, Yoshiya, Okayasu, Ryuichi, Fujimori, Akira, Durante, Marco, Nickoloff, Jac A.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2015
Sujets:
Oncology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670845/
https://ncbi.nlm.nih.gov/pubmed/26697402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00260
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