Nuclear Compartmentalization of α1-Adrenergic Receptor Signaling in Adult Cardiac Myocytes

Por Wu, Steven C., O'Connell, Timothy D.
Publicado no J Cardiovasc Pharmacol (2015)

Alpha-1-Adrenergic Receptors: Targets for Agonist Drugs to Treat Heart Failure

Por Jensen, Brian C., O'Connell, Timothy D., Simpson, Paul C.
Publicado em 2010

Alpha-1-Adrenergic Receptors in Heart Failure: The Adaptive Arm of the Cardiac Response to Chronic Catecholamine Stimulation

Por Jensen, Brian C., O'Connell, Timothy D., Simpson, Paul C.
Publicado em 2014

Cardiac Alpha(1)-Adrenergic Receptors: Novel Aspects of Expression, Signaling Mechanisms, Physiologic Function, and Clinical Importance

Por O’Connell, Timothy D., Jensen, Brian C., Baker, Anthony J., Simpson, Paul C.
Publicado em 2014

ω3-Polyunsaturated Fatty Acids for Heart Failure: Effects of Dose on Efficacy and Novel Signaling through Free Fatty Acid Receptor 4

Por O’Connell, Timothy D., Block, Robert C., Huang, Shue P., Shearer, Gregory C.
Publicado no J Mol Cell Cardiol (2016)

Nuclear Localization Drives α1-Adrenergic Receptor Oligomerization and Signaling in Cardiac Myocytes

Por Wright, Casey D., Wu, Steven C., Dahl, Erika F., Sazama, Alan J., O’Connell, Timothy D.
Publicado em 2011

Mechanistic insights into cardiovascular protection for omega-3 fatty acids and their bioactive lipid metabolites

Por O’Connell, Timothy D, Mason, Richard Preston, Budoff, Matthew J, Navar, Ann Marie, Shearer, Gregory C
Publicado no Eur Heart J Suppl (2020)

An Association Between Gene Expression and Better Survival in Female Mice Following Myocardial Infarction

Por Chen, Quanhai, Williams, Roy, Healy, Chastity L., Wright, Casey D., Wu, Steven C., O’Connell, Timothy D.
Publicado em 2010

Nuclear α1-Adrenergic Receptors Signal Activated ERK Localization to Caveolae in Adult Cardiac Myocytes

Por Wright, Casey D., Chen, Quanhai, Baye, Nichole L., Huang, Yuan, Healy, Chastity L., Kasinathan, Sivakanthan, O’Connell, Timothy D.
Publicado em 2008

Nuclear Localization of α1A‐Adrenergic Receptors Is Required for Signaling in Cardiac Myocytes: An “Inside‐Out” α1‐AR Signaling Pathway

Por Wu, Steven C., Dahl, Erika F., Wright, Casey D., Cypher, Andrew L., Healy, Chastity L., O'Connell, Timothy D.
Publicado em 2014

Subcellular compartmentalization of proximal Gα(q)-receptor signaling produces unique hypertrophic phenotypes in adult cardiac myocytes

Por Dahl, Erika F., Wu, Steven C., Healy, Chastity L., Harsch, Brian A., Shearer, Gregory C., O'Connell, Timothy D.
Publicado no J Biol Chem (2018)

GATA4 is a survival factor in adult cardiac myocytes but is not required for α1A-adrenergic receptor survival signaling

Por Huang, Yuan, Wright, Casey D., Kobayashi, Satoru, Healy, Chastity L., Elgethun, Megan, Cypher, Andrew, Liang, Qiangrong, O'Connell, Timothy D.
Publicado em 2008

ω-3 fatty acids prevent pressure overload-induced cardiac fibrosis through activation of cGMP/PKG signaling in cardiac fibroblasts

Por Chen, Jinghai, Shearer, Gregory C., Chen, Quanhai, Healy, Chastity L., Beyer, April J., Nareddy, Vijaya B., Gerdes, A. Martin, Harris, William S., O’Connell, Timothy D., Wang, Dajun
Publicado em 2011

EPA, not DHA, prevents fibrosis in pressure overload-induced heart failure: potential role of free fatty acid receptor 4

Por Eclov, Julie A., Qian, Qingwen, Redetzke, Rebecca, Chen, Quanhai, Wu, Steven C., Healy, Chastity L., Ortmeier, Steven B., Harmon, Erin, Shearer, Gregory C., O’Connell, Timothy D.
Publicado no J Lipid Res (2015)

Derivation and High Engraftment of Patient-Specific Cardiomyocyte-Sheet Using Induced Pluripotent Stem Cells Generated From Adult Cardiac Fibroblast

Por Zhang, Liying, Guo, Jing, Zhang, Pengyuan, Xiong, Qiang, Wu, Steven C., Xia, Lily, Roy, Samit Sunny, Tolar, Jakub, O'Connell, Timothy D., Kyba, Michael, Liao, Kenneth, Zhang, Jianyi
Publicado no Circ Heart Fail (2014)

The α(1A/C)- and α(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse

Por O’Connell, Timothy D., Ishizaka, Shinji, Nakamura, Akihiro, Swigart, Philip M., Rodrigo, M.C., Simpson, Gregory L., Cotecchia, Susanna, Rokosh, D. Gregg, Grossman, William, Foster, Elyse, Simpson, Paul C.
Publicado em 2003

α(1)-Adrenergic receptors prevent a maladaptive cardiac response to pressure overload

Por O’Connell, Timothy D., Swigart, Philip M., Rodrigo, M.C., Ishizaka, Shinji, Joho, Shuji, Turnbull, Lynne, Tecott, Laurence H., Baker, Anthony J., Foster, Elyse, Grossman, William, Simpson, Paul C.
Publicado em 2006