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Cardiac Alpha(1)-Adrenergic Receptors: Novel Aspects of Expression, Signaling Mechanisms, Physiologic Function, and Clinical Importance
Adrenergic receptors (AR) are G-protein-coupled receptors (GPCRs) that have a crucial role in cardiac physiology in health and disease. Alpha(1)-ARs signal through Gα(q), and signaling through G(q), for example, by endothelin and angiotensin receptors, is thought to be detrimental to the heart. In c...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3880467/ https://ncbi.nlm.nih.gov/pubmed/24368739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.112.007203 |
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