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Cardiac Alpha(1)-Adrenergic Receptors: Novel Aspects of Expression, Signaling Mechanisms, Physiologic Function, and Clinical Importance

Adrenergic receptors (AR) are G-protein-coupled receptors (GPCRs) that have a crucial role in cardiac physiology in health and disease. Alpha(1)-ARs signal through Gα(q), and signaling through G(q), for example, by endothelin and angiotensin receptors, is thought to be detrimental to the heart. In c...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: O’Connell, Timothy D., Jensen, Brian C., Baker, Anthony J., Simpson, Paul C.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The American Society for Pharmacology and Experimental Therapeutics 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880467/
https://ncbi.nlm.nih.gov/pubmed/24368739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.112.007203
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