The α(1A/C)- and α(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse

Catecholamines and α(1)-adrenergic receptors (α(1)-ARs) cause cardiac hypertrophy in cultured myocytes and transgenic mice, but heart size is normal in single KOs of the main α(1)-AR subtypes, α(1A/C) and α(1B). Here we tested whether α(1)-ARs are required for developmental cardiac hypertrophy by ge...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	O’Connell, Timothy D., Ishizaka, Shinji, Nakamura, Akihiro, Swigart, Philip M., Rodrigo, M.C., Simpson, Gregory L., Cotecchia, Susanna, Rokosh, D. Gregg, Grossman, William, Foster, Elyse, Simpson, Paul C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2003
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156101/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12782680/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI16100
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