Cutting Edge: The Orphan Nuclear Receptor Nr4a1 Regulates CD8(+) T Cell Expansion and Effector Function through Direct Repression of Irf4

Por Nowyhed, Heba N., Huynh, Tridu R., Thomas, Graham D., Blatchley, Amy, Hedrick, Catherine C.
Publicado no J Immunol (2015)

Development of a nanoparticulate formulation of retinoic acid that suppresses Th17 cells and upregulates regulatory T cells

Por Capurso, Noah A, Look, Michael, Jeanbart, Laura, Nowyhed, Heba, Abraham, Clara, Craft, Joe, Fahmy, Tarek M
Publicado em 2010

The Nuclear Receptor Nr4a1 Controls CD8 T Cell Development Through Transcriptional Suppression of Runx3

Por Nowyhed, Heba N., Huynh, Tridu R., Blatchley, Amy, Wu, Runpei, Thomas, Graham D., Hedrick, Catherine C.
Publicado no Sci Rep (2015)

NR4A Nuclear Receptors in Immunity and Atherosclerosis

Por Hamers, Anouk A.J., Hanna, Richard N., Nowyhed, Heba, Hedrick, Catherine C., de Vries, Carlie J.M.
Publicado no Curr Opin Lipidol (2013)

ATP-Binding Cassette Transporter G1 Intrinsically Regulates Invariant NKT Cell Development

Por Sag, Duygu, Wingender, Gerhard, Nowyhed, Heba, Wu, Runpei, Gebre, Abraham K., Parks, John S., Kronenberg, Mitchell, Hedrick, Catherine C.
Publicado em 2012

B cells in T Follicular Helper Cell Development and Function: Separable Roles in Delivery of ICOS Ligand and Antigen

Por Weinstein, Jason S., Bertino, Sarah A., Hernandez, Sairy G., Poholek, Amanda C., Teplitzky, Taylor B., Nowyhed, Heba N., Craft, Joe
Publicado em 2014

Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation

Por Marks, Benjamin R., Nowyhed, Heba N., Choi, Jin-Young, Poholek, Amanda C., Odegard, Jared M., Flavell, Richard A., Craft, Joe
Publicado em 2009

SAMP1/YitFc Mice Develop Ileitis via Loss of CCL21 and Defects in Dendritic Cell Migration

Por Mikulski, Zbigniew, Johnson, Rebecca, Shaked, Iftach, Kim, Gisen, Nowyhed, Heba, Goodman, Wendy, Chodaczek, Grzegorz, Pizarro, Theresa T., Cominelli, Fabio, Ley, Klaus
Publicado no Gastroenterology (2015)

ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content

Por Nowyhed, Heba N., Chandra, Shilpi, Kiosses, William, Marcovecchio, Paola, Andary, Farah, Zhao, Meng, Fitzgerald, Michael L., Kronenberg, Mitchell, Hedrick, Catherine C.
Publicado no Sci Rep (2017)

The transcription factor NR4A1 is essential for the development of a novel macrophage subset in the thymus

Por Tacke, Robert, Hilgendorf, Ingo, Garner, Hannah, Waterborg, Claire, Park, Kiwon, Nowyhed, Heba, Hanna, Richard N., Wu, Runpei, Swirski, Filip K., Geissmann, Frederic, Hedrick, Catherine C.
Publicado no Sci Rep (2015)

ABC transporters and NR4A1 identify a quiescent subset of tissue-resident memory T cells

Por Boddupalli, Chandra Sekhar, Nair, Shiny, Gray, Simon M., Nowyhed, Heba N., Verma, Rakesh, Gibson, Joanna A., Abraham, Clara, Narayan, Deepak, Vasquez, Juan, Hedrick, Catherine C., Flavell, Richard A., Dhodapkar, Kavita M., Kaech, Susan M., Dhodapkar, Madhav V.
Publicado no J Clin Invest (2016)

Patrolling Monocytes Control Tumor Metastasis to the Lung

Por Hanna, Richard N., Cekic, Caglar, Sag, Duygu, Tacke, Robert, Thomas, Graham D., Nowyhed, Heba, Herrley, Erica, Rasquinha, Nicole, McArdle, Sara, Wu, Runpei, Peluso, Esther, Metzger, Daniel, Ichinose, Hiroshi, Shaked, Iftach, Chodaczek, Grzegorz, Biswas, Subhra K., Hedrick, Catherine C.
Publicado no Science (2015)

The orphan nuclear receptor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation

Por Shaked, Iftach, Hanna, Richard N., Shaked, Helena, Chodaczek, Grzegorz, Nowyhed, Heba N., Tweet, George, Tacke, Robert, Basat, Alp Bugra, Mikulski, Zbigniew, Togher, Susan, Miller, Jacqueline, Blatchley, Amy, Salek-Ardakani, Shahram, Darvas, Martin, Kaikkonen, Minna U., Thomas, Graham, Lai-Wing-Sun, Sonia, Rezk, Ayman, Bar-Or, Amit, Glass, Christopher K., Bandukwala, Hozefa, Hedrick, Catherine C.
Publicado no Nat Immunol (2015)