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ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content

ABCA7 is an ABC transporter expressed on the plasma membrane, and actively exports phospholipid complexes from the cytoplasmic to the exocytoplasmic leaflet of membranes. Invariant NKT (iNKT) cells are a subpopulation of T lymphocytes that recognize glycolipid antigens in the context of CD1d-mediate...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nowyhed, Heba N., Chandra, Shilpi, Kiosses, William, Marcovecchio, Paola, Andary, Farah, Zhao, Meng, Fitzgerald, Michael L., Kronenberg, Mitchell, Hedrick, Catherine C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238393/
https://ncbi.nlm.nih.gov/pubmed/28091533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40273
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