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ATP-binding cassette transporter-2 (ABCA2) as a therapeutic target
The ATP binding cassette transporter ABCA2 is primarily an endolysosomal membrane protein that demonstrates pleiotropic functionalities, coalescing around the maintenance of homeostasis of sterols, sphingolipids and cholesterol. It is most highly expressed in brain tissue and ABCA2 knockout mice exp...
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| Pubblicato in: | Biochem Pharmacol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5899931/ https://ncbi.nlm.nih.gov/pubmed/29223352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.11.018 |
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