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ATP-binding cassette transporter-2 (ABCA2) as a therapeutic target

The ATP binding cassette transporter ABCA2 is primarily an endolysosomal membrane protein that demonstrates pleiotropic functionalities, coalescing around the maintenance of homeostasis of sterols, sphingolipids and cholesterol. It is most highly expressed in brain tissue and ABCA2 knockout mice exp...

詳細記述

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書誌詳細
出版年:Biochem Pharmacol
主要な著者: Davis, Warren, Tew, Kenneth D.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899931/
https://ncbi.nlm.nih.gov/pubmed/29223352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.11.018
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