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Ablation of the ATP-binding cassette transporter, Abca2 modifies response to estrogen-based therapies

The ATP-binding cassette transporter 2 (ABCA2) is an endolysosomal protein expressed in oligodendrocytes and Schwann cells, prostate, ovary and macrophages. In cell cultures, ABCA2 over-expression has been linked with resistance to the anticancer agent, estramustine phosphate (EMP; a nor-nitrogen mu...

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Autori principali: Mack, Jody T., Brown, Carol B., Garrett, Tracy E., Uys, Joachim D., Townsend, Danyelle M., Tew, Kenneth D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714854/
https://ncbi.nlm.nih.gov/pubmed/22898081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopha.2012.06.007
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