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Ablation of the ATP-binding cassette transporter, Abca2 modifies response to estrogen-based therapies
The ATP-binding cassette transporter 2 (ABCA2) is an endolysosomal protein expressed in oligodendrocytes and Schwann cells, prostate, ovary and macrophages. In cell cultures, ABCA2 over-expression has been linked with resistance to the anticancer agent, estramustine phosphate (EMP; a nor-nitrogen mu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3714854/ https://ncbi.nlm.nih.gov/pubmed/22898081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopha.2012.06.007 |
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