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“Skittish” Abca2 Knockout Mice Display Tremor, Hyperactivity, and Abnormal Myelin Ultrastructure in the Central Nervous System

The ATP-binding cassette transporter 2 (ABCA2) is an endolysosomal protein most highly expressed in the central and peripheral nervous system tissues and macrophages. Previous studies indicated its role in cholesterol/steroid (estramustine, estradiol, and progesterone) trafficking/sequestration, oxi...

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Hlavní autoři: Mack, Jody T., Beljanski, Vladimir, Soulika, Athena M., Townsend, Danyelle M., Brown, Carol B., Davis, Warren, Tew, Kenneth D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800669/
https://ncbi.nlm.nih.gov/pubmed/17060448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01824-06
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