SAMP1/YitFc Mice Develop Ileitis via Loss of CCL21 and Defects in Dendritic Cell Migration

BACKGROUND & AIMS: The lymphatic chemokine CCL21 is required for dendritic cell (DC) migration from tissues to lymph nodes, which helps establish tolerance to foreign yet harmless antigens. We demonstrate that CCL21 is almost completely absent from SAMP1/YitFc (SAMP) mice, which spontaneously de...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Gastroenterology
Main Authors: Mikulski, Zbigniew, Johnson, Rebecca, Shaked, Iftach, Kim, Gisen, Nowyhed, Heba, Goodman, Wendy, Chodaczek, Grzegorz, Pizarro, Theresa T., Cominelli, Fabio, Ley, Klaus
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375031/
https://ncbi.nlm.nih.gov/pubmed/25620669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.01.027
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki