Dysregulated Intrahepatic CD4(+) T-Cell Activation Drives Liver Inflammation in Ileitis-Prone SAMP1/YitFc Mice

BACKGROUND & AIMS: Liver inflammation is a common extraintestinal manifestation of inflammatory bowel disease (IBD), but whether liver involvement is a consequence of a primary intestinal defect or results from alternative pathogenic processes remains unclear. Therefore, we sought to determine t...

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Publicado en:Cell Mol Gastroenterol Hepatol
Autores principales: Omenetti, Sara, Brogi, Marco, Goodman, Wendy A., Croniger, Colleen M., Eid, Saada, Huang, Alex Y., Laffi, Giacomo, Roskams, Tania, Cominelli, Fabio, Pinzani, Massimo, Pizarro, Theresa T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2015
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511857/
https://ncbi.nlm.nih.gov/pubmed/26213712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2015.05.007
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