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B cells in T Follicular Helper Cell Development and Function: Separable Roles in Delivery of ICOS Ligand and Antigen

B cells are required for follicular helper T (Tfh) cell development, as is the ligand for ICOS (ICOS-L); however, the separable contributions of Ag and ICOS-L delivery by cognate B cells to Tfh-cell development and function are unknown. We find that Tfh-cell and germinal center differentiation are d...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Weinstein, Jason S., Bertino, Sarah A., Hernandez, Sairy G., Poholek, Amanda C., Teplitzky, Taylor B., Nowyhed, Heba N., Craft, Joe
פורמט: Artigo
שפה:Inglês
יצא לאור: 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991608/
https://ncbi.nlm.nih.gov/pubmed/24610013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302617
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