A Streamlined, Automated Protocol for the Production of Milligram Quantities of Untagged Recombinant Rat Lactate Dehydrogenase A Using ÄKTAxpress(TM)

Por Nowicki, Matthew W., Blackburn, Elizabeth A., McNae, Iain W., Wear, Martin A.
Publicado no PLoS One (2015)

Thermo‐kinetic analysis space expansion for cyclophilin‐ligand interactions – identification of a new nonpeptide inhibitor using Biacore™ T200

Por Wear, Martin A., Nowicki, Matthew W., Blackburn, Elizabeth A., McNae, Iain W., Walkinshaw, Malcolm D.
Publicado no FEBS Open Bio (2017)

The RFTS Domain of Raf2 Is Required for Cul4 Interaction and Heterochromatin Integrity in Fission Yeast

Por White, Sharon A., Buscaino, Alessia, Sanchez-Pulido, Luis, Ponting, Chris P., Nowicki, Matthew W., Allshire, Robin C.
Publicado em 2014

Development of a fluorescent monoclonal antibody-based assay to measure the allosteric effects of synthetic peptides on self-oligomerization of AGR2 protein

Por Gray, Terry A, Murray, Euan, Nowicki, Matthew W, Remnant, Lucy, Scherl, Alexander, Muller, Petr, Vojtesek, Borek, Hupp, Ted R
Publicado em 2013

Allosteric Mechanism of Pyruvate Kinase from Leishmania mexicana Uses a Rock and Lock Model

Por Morgan, Hugh P., McNae, Iain W., Nowicki, Matthew W., Hannaert, Véronique, Michels, Paul A. M., Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D.
Publicado em 2010

The Trypanocidal Drug Suramin and Other Trypan Blue Mimetics Are Inhibitors of Pyruvate Kinases and Bind to the Adenosine Site

Por Morgan, Hugh P., McNae, Iain W., Nowicki, Matthew W., Zhong, Wenhe, Michels, Paul A. M., Auld, Douglas S., Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D.
Publicado em 2011

High Throughput Screens Yield Small Molecule Inhibitors of Leishmania CRK3:CYC6 Cyclin-Dependent Kinase

Por Walker, Roderick G., Thomson, Graeme, Malone, Kirk, Nowicki, Matthew W., Brown, Elaine, Blake, David G., Turner, Nicholas J., Walkinshaw, Malcolm D., Grant, Karen M., Mottram, Jeremy C.
Publicado em 2011

Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation

Por Soukarieh, Fadi, Nowicki, Matthew W., Bastide, Amandine, Pöyry, Tuija, Jones, Carolyn, Dudek, Kate, Patwardhan, Geetanjali, Meullenet, François, Oldham, Neil J., Walkinshaw, Malcolm D., Willis, Anne E., Fischer, Peter M.
Publicado no Eur J Med Chem (2016)

A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinase

Por Morgan, Hugh P., Walsh, Martin J., Blackburn, Elizabeth A., Wear, Martin A., Boxer, Matthew B., Shen, Min, Mcnae, Iain W., Nowicki, Matthew W., Michels, Paul A. M., Auld, Douglas S., Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D.
Publicado em 2012