The worm sheds light on anesthetic mechanisms

Por Singaram, Vinod K., Morgan, Philip G., Sedensky, Margaret M.
Publicado em 2012

Region-Specific Defects of Respiratory Capacities in the Ndufs4(KO) Mouse Brain

Por Kayser, Ernst-Bernhard, Sedensky, Margaret M., Morgan, Philip G.
Publicado no PLoS One (2016)

Early Developmental Exposure to Volatile Anesthetics Causes Behavioral Defects in Caenorhabditis elegans

Por Gentry, Katherine R., Steele, Louise M., Sedensky, Margaret M., Morgan, Philip G.
Publicado em 2012

Mitochondrial Complex I Function Modulates Volatile Anesthetic Sensitivity in C. elegans

Por Falk, Marni J., Kayser, Ernst-Bernhard, Morgan, Philip G., Sedensky, Margaret M.
Publicado em 2006

Novel Interactions between Mitochondrial Superoxide Dismutases and the Electron Transport Chain

Por Suthammarak, Wichit, Somerlot, Benjamin H., Opheim, Elyce, Sedensky, Margaret, Morgan, Philip G.
Publicado em 2013

Anesthetics have different effects on the electrocorticographic spectra of wildtype and mitochondrial mutant mice

Por Carspecken, Charles William, Chanprasert, Sirisak, Kalume, Franck, Sedensky, Margaret M., Morgan, Philip G.
Publicado no Anesthesiology (2018)

Mitochondrial Function in Astrocytes is Essential for Normal Emergence from Anesthesia in Mice

Por Ramadasan-Nair, Renjini, Hui, Jessica, Itsara, Leslie S, Morgan, Philip G, Sedensky, Margaret M
Publicado no Anesthesiology (2019)

Altered Anesthetic Sensitivity of Mice Lacking Ndufs4, a Subunit of Mitochondrial Complex I

Por Quintana, Albert, Morgan, Philip G., Kruse, Shane E., Palmiter, Richard D., Sedensky, Margaret M.
Publicado em 2012

Glutathione S-transferase mediates an ageing response to mitochondrial dysfunction

Por Dancy, Beverley M., Brockway, Nicole, Ramadasan-Nair, Renjini, Yang, Yoing, Sedensky, Margaret M., Morgan, Philip G.
Publicado no Mech Ageing Dev (2015)

Regional knockdown of NDUFS4 implicates a thalamocortical circuit mediating anesthetic sensitivity

Por Ramadasan-Nair, Renjini, Hui, Jessica, Zimin, Pavel I., Itsara, Leslie S., Morgan, Philip G., Sedensky, Margaret M.
Publicado no PLoS One (2017)

Glutamatergic neurotransmission links sensitivity to volatile anesthetics with mitochondrial function

Por Zimin, Pavel I., Woods, Christian B., Quintana, Albert, Ramirez, Jan-Marino, Morgan, Philip G., Sedensky, Margaret M.
Publicado no Curr Biol (2016)

The Genetics of Isoflurane-induced Developmental Neurotoxicity

Por Na, Hyo-Seok, Brockway, Nicole L, Gentry, Katherine R, Opheim, Elyce, Sedensky, Margaret M, Morgan, Philip G
Publicado no Neurotoxicol Teratol (2016)

Optical reversal of halothane-induced immobility in C. elegans

Por Singaram, Vinod K., Somerlot, Benjamin H., Falk, Scott A., Falk, Marni J., Sedensky, Margaret M., Morgan, Philip G.
Publicado em 2011

AGING AND MITOCHONDRIAL DISEASE: SHARED MECHANISMS AND THERAPIES?

Por Bitto, Alessandro, Tung, Herman, Ying, Kejun, Smith, Daniel L, Kayser, Ernst-Bernhard, Morgan, Philip G, Sedensky, Margaret M, Kaeberlein, Matt
Publicado no Innov Aging (2019)

A Drosophila model of mitochondrial disease caused by a complex I mutation that uncouples proton pumping from electron transfer

Por Burman, Jonathon L., Itsara, Leslie S., Kayser, Ernst-Bernhard, Suthammarak, Wichit, Wang, Adrienne M., Kaeberlein, Matt, Sedensky, Margaret M., Morgan, Philip G., Pallanck, Leo J.
Publicado em 2014

Mitochondrial Complex I Deficiency Increases Protein Acetylation and Accelerates Heart Failure

Por Karamanlidis, Georgios, Lee, Chi Fung, Garcia-Menendez, Lorena, Kolwicz, Stephen C., Suthammarak, Wichit, Gong, Guohua, Sedensky, Margaret M., Morgan, Philip G., Wang, Wang, Tian, Rong
Publicado em 2013

Regional metabolic signatures in the Ndufs4(KO) mouse brain implicate defective glutamate/α-ketoglutarate metabolism in mitochondrial disease

Por Johnson, Simon C., Kayser, Ernst-Bernhard, Bornstein, Rebecca, Stokes, Julia, Bitto, Alessandro, Park, Kyung Yeon, Pan, Amanda, Sun, Grace, Raftery, Daniel, Kaeberlein, Matt, Sedensky, Margaret M, Morgan, Philip G
Publicado no Mol Genet Metab (2020)

Relevance of experimental paradigms of anesthesia induced neurotoxicity in the mouse

Por Johnson, Simon C., Pan, Amanda, Sun, Grace X., Freed, Arielle, Stokes, Julia C., Bornstein, Rebecca, Witkowski, Michael, Li, Li, Ford, Jeremy M., Howard, Christopher R. A., Sedensky, Margaret M., Morgan, Philip G.
Publicado no PLoS One (2019)

mTOR inhibitors may benefit kidney transplant recipients with mitochondrial diseases

Por Johnson, Simon C., Martinez, Frank, Bitto, Alessandro, Gonzalez, Brenda, Tazaerslan, Cagdas, Cohen, Camille, Delaval, Laure, Timsit, José, Knebelmann, Bertrand, Terzi, Fabiola, Mahal, Tarika, Zhu, Yizhou, Morgan, Philip G., Sedensky, Margaret M., Kaeberlein, Matt, Legendre, Christophe, Suh, Yousin, Canaud, Guillaume
Publicado no Kidney Int (2018)

Caenorhabditis elegans UCP4 Protein Controls Complex II-mediated Oxidative Phosphorylation through Succinate Transport

Por Pfeiffer, Matthew, Kayzer, Ernst-Bernhard, Yang, Xianmei, Abramson, Ellen, Kenaston, M. Alexander, Lago, Cory U., Lo, Herng-Hsiang, Sedensky, Margaret M., Lunceford, Adam, Clarke, Catherine F., Wu, Sarah J., McLeod, Chris, Finkel, Toren, Morgan, Philip G., Mills, Edward M.
Publicado em 2011