IS AGING AN ACQUIRED MITOCHONDRIAL DISEASE?

Autor Bitto, Alessandro
Vydáno v Innov Aging (2019)

Rejuvenation: It’s in our blood

Autor Bitto, Alessandro, Kaeberlein, Matt
Vydáno 2014

Protein Kinase C Downregulation upon Rapamycin Treatment Attenuates Neuroinflammation and Mitochondrial Disease

Autor Grillo, Anthony, Bitto, Alessandro, Kaeberlein, Matt
Vydáno v Innov Aging (2020)

Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh Syndrome

Autor Bitto, Alessandro, Grillo, Anthony, Kaeberlein, Matt
Vydáno v Innov Aging (2020)

Proceedings from the annual University of Washington Geroscience Symposium, October 23, 2020

Autor Lee, Mitchell B., Bitto, Alessandro, Kaeberlein, Matt
Vydáno v GeroScience (2021)

Biochemical Genetic Pathways that Modulate Aging in Multiple Species

Autor Bitto, Alessandro, Wang, Adrienne M., Bennett, Christopher F., Kaeberlein, Matt
Vydáno v Cold Spring Harb Perspect Med (2015)

The importance of diversity and outreach in geroscience research: Insights from the Annual Biomedical Research Conference for Minority Students

Autor Lee, Mitchell B., Datta, Dibyadeep, Hill, Cristal M., Bitto, Alessandro
Vydáno v GeroScience (2020)

p62/SQSTM1 at the interface of aging, autophagy, and disease

Autor Bitto, Alessandro, Lerner, Chad A., Nacarelli, Timothy, Crowe, Elizabeth, Torres, Claudio, Sell, Christian
Vydáno 2014

Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts

Autor Lerner, Chad, Bitto, Alessandro, Pulliam, Daniel, Nacarelli, Timothy, Konigsberg, Mina, Van Remmen, Holly, Torres, Claudio, Sell, Christian
Vydáno v Aging Cell (2013)

AGING AND MITOCHONDRIAL DISEASE: SHARED MECHANISMS AND THERAPIES?

Autor Bitto, Alessandro, Tung, Herman, Ying, Kejun, Smith, Daniel L, Kayser, Ernst-Bernhard, Morgan, Philip G, Sedensky, Margaret M, Kaeberlein, Matt
Vydáno v Innov Aging (2019)

Astrocyte Senescence as a Component of Alzheimer’s Disease

Autor Bhat, Rekha, Crowe, Elizabeth P., Bitto, Alessandro, Moh, Michelle, Katsetos, Christos D., Garcia, Fernando U., Johnson, Frederick Bradley, Trojanowski, John Q., Sell, Christian, Torres, Claudio
Vydáno 2012

Long-Term IGF-I Exposure Decreases Autophagy and Cell Viability

Autor Bitto, Alessandro, Lerner, Chad, Torres, Claudio, Roell, Michaela, Malaguti, Marco, Perez, Viviana, Lorenzini, Antonello, Hrelia, Silvana, Ikeno, Yuji, Matzko, Michelle Elizabeth, McCarter, Roger, Sell, Christian
Vydáno 2010

Proepithelin Regulates Prostate Cancer Cell Biology by Promoting Cell Growth, Migration, and Anchorage-Independent Growth

Autor Monami, Giada, Emiliozzi, Velia, Bitto, Alessandro, Lovat, Francesca, Xu, Shi-Qiong, Goldoni, Silvia, Fassan, Matteo, Serrero, Ginette, Gomella, Leonard G., Baffa, Raffaele, Iozzo, Renato V., Morrione, Andrea
Vydáno 2009

Regional metabolic signatures in the Ndufs4(KO) mouse brain implicate defective glutamate/α-ketoglutarate metabolism in mitochondrial disease

Autor Johnson, Simon C., Kayser, Ernst-Bernhard, Bornstein, Rebecca, Stokes, Julia, Bitto, Alessandro, Park, Kyung Yeon, Pan, Amanda, Sun, Grace, Raftery, Daniel, Kaeberlein, Matt, Sedensky, Margaret M, Morgan, Philip G
Vydáno v Mol Genet Metab (2020)

Proepithelin is an autocrine growth factor for bladder cancer

Autor Lovat, Francesca, Bitto, Alessandro, Xu, Shi-Qiong, Fassan, Matteo, Goldoni, Silvia, Metalli, David, Wubah, Vera, McCue, Peter, Serrero, Ginette, Gomella, Leonard G., Baffa, Raffaele, Iozzo, Renato V., Morrione, Andrea
Vydáno 2009

SS‐31 and NMN: Two paths to improve metabolism and function in aged hearts

Autor Whitson, Jeremy A., Bitto, Alessandro, Zhang, Huiliang, Sweetwyne, Mariya T., Coig, Rene, Bhayana, Saakshi, Shankland, Eric G., Wang, Lu, Bammler, Theo K., Mills, Kathryn F., Imai, Shin‐Ichiro, Conley, Kevin E., Marcinek, David J., Rabinovitch, Peter S.
Vydáno v Aging Cell (2020)

mTOR inhibitors may benefit kidney transplant recipients with mitochondrial diseases

Autor Johnson, Simon C., Martinez, Frank, Bitto, Alessandro, Gonzalez, Brenda, Tazaerslan, Cagdas, Cohen, Camille, Delaval, Laure, Timsit, José, Knebelmann, Bertrand, Terzi, Fabiola, Mahal, Tarika, Zhu, Yizhou, Morgan, Philip G., Sedensky, Margaret M., Kaeberlein, Matt, Legendre, Christophe, Suh, Yousin, Canaud, Guillaume
Vydáno v Kidney Int (2018)

Dose-dependent effects of mTOR inhibition on weight and mitochondrial disease in mice

Autor Johnson, Simon C., Yanos, Melana E., Bitto, Alessandro, Castanza, Anthony, Gagnidze, Arni, Gonzalez, Brenda, Gupta, Kanav, Hui, Jessica, Jarvie, Conner, Johnson, Brittany M., Letexier, Nicolas, McCanta, Lanny, Sangesland, Maya, Tamis, Oliver, Uhde, Lauren, Van Den Ende, Alex, Rabinovitch, Peter S., Suh, Yousin, Kaeberlein, Matt
Vydáno v Front Genet (2015)

Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice

Autor Bitto, Alessandro, Ito, Takashi K, Pineda, Victor V, LeTexier, Nicolas J, Huang, Heather Z, Sutlief, Elissa, Tung, Herman, Vizzini, Nicholas, Chen, Belle, Smith, Kaleb, Meza, Daniel, Yajima, Masanao, Beyer, Richard P, Kerr, Kathleen F, Davis, Daniel J, Gillespie, Catherine H, Snyder, Jessica M, Treuting, Piper M, Kaeberlein, Matt
Vydáno v eLife (2016)

Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency

Autor Ito, Takashi K., Lu, Chenhao, Khan, Jacob, Nguyen, Quy, Huang, Heather Z., Kim, Dayae, Phillips, James, Tan, Jo, Lee, Yenna, Nguyen, Tuyet, Khessib, Samy, Lim, Natalie, Mekvanich, Surapat, Oh, Joshua, Pineda, Victor V., Wang, Weirong, Bitto, Alessandro, An, Jonathan Y., Morton, John F., Setou, Mitsutoshi, Ladiges, Warren C., Kaeberlein, Matt
Vydáno v Front Genet (2017)