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Long-Term IGF-I Exposure Decreases Autophagy and Cell Viability
A reduction in IGF-I signaling has been found to increase lifespan in multiple organisms despite the fact that IGF-I is a trophic factor for many cell types and has been found to have protective effects against multiple forms of damage in acute settings. The increase in longevity seen in response to...
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| Główni autorzy: | , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2935370/ https://ncbi.nlm.nih.gov/pubmed/20830296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012592 |
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