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SS‐31 and NMN: Two paths to improve metabolism and function in aged hearts

The effects of two different mitochondrial‐targeted drugs, SS‐31 and NMN, were tested on Old mouse hearts. After treatment with the drugs, individually or Combined, heart function was examined by echocardiography. SS‐31 partially reversed an age‐related decline in diastolic function while NMN fully...

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書目詳細資料
發表在:Aging Cell
Main Authors: Whitson, Jeremy A., Bitto, Alessandro, Zhang, Huiliang, Sweetwyne, Mariya T., Coig, Rene, Bhayana, Saakshi, Shankland, Eric G., Wang, Lu, Bammler, Theo K., Mills, Kathryn F., Imai, Shin‐Ichiro, Conley, Kevin E., Marcinek, David J., Rabinovitch, Peter S.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576234/
https://ncbi.nlm.nih.gov/pubmed/32779818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13213
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