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The Mitochondrial-Targeted Compound SS-31 Re-Energizes Ischemic Mitochondria by Interacting with Cardiolipin

Ischemia causes AKI as a result of ATP depletion, and rapid recovery of ATP on reperfusion is important to minimize tissue damage. ATP recovery is often delayed, however, because ischemia destroys the mitochondrial cristae membranes required for mitochondrial ATP synthesis. The mitochondria-targeted...

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Detalhes bibliográficos
Main Authors: Birk, Alexander V., Liu, Shaoyi, Soong, Yi, Mills, William, Singh, Pradeep, Warren, J. David, Seshan, Surya V., Pardee, Joel D., Szeto, Hazel H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736700/
https://ncbi.nlm.nih.gov/pubmed/23813215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012121216
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