The Mitochondrial-Targeted Compound SS-31 Re-Energizes Ischemic Mitochondria by Interacting with Cardiolipin

Ischemia causes AKI as a result of ATP depletion, and rapid recovery of ATP on reperfusion is important to minimize tissue damage. ATP recovery is often delayed, however, because ischemia destroys the mitochondrial cristae membranes required for mitochondrial ATP synthesis. The mitochondria-targeted...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Birk, Alexander V., Liu, Shaoyi, Soong, Yi, Mills, William, Singh, Pradeep, Warren, J. David, Seshan, Surya V., Pardee, Joel D., Szeto, Hazel H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Nephrology 2013
Gaiak:
Basic Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736700/
https://ncbi.nlm.nih.gov/pubmed/23813215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012121216
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