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Targeting mitochondrial cardiolipin and the cytochrome c/cardiolipin complex to promote electron transport and optimize mitochondrial ATP synthesis

BACKGROUND AND PURPOSE: Cardiolipin plays an important role in mitochondrial respiration and cardiolipin peroxidation is associated with age-related diseases. Hydrophobic interactions between cytochrome c and cardiolipin converts cytochrome c from an electron carrier to a peroxidase. In addition to...

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主要な著者: Birk, A V, Chao, W M, Bracken, C, Warren, J D, Szeto, H H
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Publishing Ltd 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976619/
https://ncbi.nlm.nih.gov/pubmed/24134698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12468
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