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The mitochondrial-targeted peptide, SS-31, improves glomerular architecture in mice of advanced age

Although age-associated changes in kidney glomerular architecture have been described in mice and man, the mechanisms are unknown. It is unclear if these changes can be prevented or even reversed by systemic therapies administered at advanced age. Using light microscopy and transmission electron mic...

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Podrobná bibliografie
Vydáno v:Kidney Int
Hlavní autoři: Sweetwyne, Mariya T., Pippin, Jeffrey W., Eng, Diana G., Hudkins, Kelly L., Chiao, Ying Ann, Campbell, Matthew D., Marcinek, David J., Alpers, Charles E., Szeto, Hazel H., Rabinovitch, Peter S., Shankland, Stuart J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392164/
https://ncbi.nlm.nih.gov/pubmed/28063595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.10.036
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