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Protein Kinase C Downregulation upon Rapamycin Treatment Attenuates Neuroinflammation and Mitochondrial Disease

Mitochondrial dysfunction causes many poorly understood diseases, such as Leigh Syndrome, that are often caused by dysfunctions in proteins involved in the electron transport chain. My lab previously reported mTOR is pathologically involved in the neurodegenerative phenotype and premature death of m...

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Detalhes bibliográficos
Publicado no:Innov Aging
Main Authors: Grillo, Anthony, Bitto, Alessandro, Kaeberlein, Matt
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7740281/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.3281
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