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Protein Kinase C Downregulation upon Rapamycin Treatment Attenuates Neuroinflammation and Mitochondrial Disease

Mitochondrial dysfunction causes many poorly understood diseases, such as Leigh Syndrome, that are often caused by dysfunctions in proteins involved in the electron transport chain. My lab previously reported mTOR is pathologically involved in the neurodegenerative phenotype and premature death of m...

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Bibliografski detalji
Izdano u:Innov Aging
Glavni autori: Grillo, Anthony, Bitto, Alessandro, Kaeberlein, Matt
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7740281/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.3281
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