Relevance of experimental paradigms of anesthesia induced neurotoxicity in the mouse

Routine general anesthesia is considered to be safe in healthy individuals. However, pre-clinical studies in mice, rats, and monkeys have repeatedly demonstrated that exposure to anesthetic agents during early post-natal periods can lead to acute neurotoxicity. More concerning, later-life defects in...

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Udgivet i:PLoS One
Main Authors: Johnson, Simon C., Pan, Amanda, Sun, Grace X., Freed, Arielle, Stokes, Julia C., Bornstein, Rebecca, Witkowski, Michael, Li, Li, Ford, Jeremy M., Howard, Christopher R. A., Sedensky, Margaret M., Morgan, Philip G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428290/
https://ncbi.nlm.nih.gov/pubmed/30897103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213543
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