Cyclophilin D Contributes to Anesthesia Neurotoxicity in the Developing Brain

Anesthetic sevoflurane induces mitochondrial dysfunction, impairment of neurogenesis, and cognitive impairment in young mice, but the underlying mechanism remains to be determined. Cyclophilin D (CypD) is a modulatory factor for the mitochondrial permeability transition pore (mPTP). We, therefore, s...

Full description

Saved in:
Bibliographic Details
Published in:Front Cell Dev Biol
Main Authors: Zhang, Yiying, Lu, Pan, Liang, Feng, Liufu, Ning, Dong, Yuanlin, Zheng, Jialin Charles, Xie, Zhongcong
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Cell and Developmental Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026027/
https://ncbi.nlm.nih.gov/pubmed/32117955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00396
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items