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Cyclophilin D Contributes to Anesthesia Neurotoxicity in the Developing Brain
Anesthetic sevoflurane induces mitochondrial dysfunction, impairment of neurogenesis, and cognitive impairment in young mice, but the underlying mechanism remains to be determined. Cyclophilin D (CypD) is a modulatory factor for the mitochondrial permeability transition pore (mPTP). We, therefore, s...
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| Publicado no: | Front Cell Dev Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7026027/ https://ncbi.nlm.nih.gov/pubmed/32117955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00396 |
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