Epigenetic Regulation of Matrix Metalloproteinase-1 and -3 Expression in Mycobacterium tuberculosis Infection

Por Moores, Rachel C., Brilha, Sara, Schutgens, Frans, Elkington, Paul T., Friedland, Jon S.
Publicado no Front Immunol (2017)

In an in vitro model of human tuberculosis, monocyte-microglial networks regulate matrix metalloproteinase-1 and -3 gene expression and secretion via a p38 mitogen activated protei...

Por Green, Justin A, Rand, Lucinda, Moores, Rachel, Dholakia, Shruti, Pezas, Theodore, Elkington, Paul T, Friedland, Jon S
Publicado em 2013

<it>Mycobacterium tuberculosis</it>-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNFα, NFκB, p38 and caspase 8 dependent pathways

Por Elkington Paul T, Fry Julie, Moores Rachel, Ong Catherine WM, Janczar Karolina, Dholakia Shruti, Green Justin A, Roncaroli Federico, Friedland Jon S
Publicado em 2011-05-01

Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNFα, NFκB, p38 and caspase 8 dependent pathways

Por Green, Justin A, Dholakia, Shruti, Janczar, Karolina, Ong, Catherine WM, Moores, Rachel, Fry, Julie, Elkington, Paul T, Roncaroli, Federico, Friedland, Jon S
Publicado em 2011

Early Secretory Antigenic Target-6 Drives Matrix Metalloproteinase-10 Gene Expression and Secretion in Tuberculosis

Por Brilha, Sara, Sathyamoorthy, Tarangini, Stuttaford, Laura H., Walker, Naomi F., Wilkinson, Robert J., Singh, Shivani, Moores, Rachel C., Elkington, Paul T., Friedland, Jon S.
Publicado no Am J Respir Cell Mol Biol (2017)

Neutrophil-Derived MMP-8 Drives AMPK-Dependent Matrix Destruction in Human Pulmonary Tuberculosis

Por Ong, Catherine W. M., Elkington, Paul T., Brilha, Sara, Ugarte-Gil, Cesar, Tome-Esteban, Maite T., Tezera, Liku B., Pabisiak, Przemyslaw J., Moores, Rachel C., Sathyamoorthy, Tarangini, Patel, Vimal, Gilman, Robert H., Porter, Joanna C., Friedland, Jon S.
Publicado no PLoS Pathog (2015)

Hypoxia and tissue destruction in pulmonary TB

Por Belton, Moerida, Brilha, Sara, Manavaki, Roido, Mauri, Francesco, Nijran, Kuldip, Hong, Young T, Patel, Neva H, Dembek, Marcin, Tezera, Liku, Green, Justin, Moores, Rachel, Aigbirhio, Franklin, Al-Nahhas, Adil, Fryer, Tim D, Elkington, Paul T, Friedland, Jon S
Publicado no Thorax (2016)