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<it>Mycobacterium tuberculosis</it>-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNFα, NFκB, p38 and caspase 8 dependent pathways
<p>Abstract</p> <p>Tuberculosis (TB) of the central nervous system (CNS) is a deadly disease characterized by extensive tissue destruction, driven by molecules such as Matrix Metalloproteinase-2 (MMP-2) which targets CNS-specific substrates. In a simplified cellular model of CNS TB...
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| Main Authors: | , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2011-05-01
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| Colecção: | Journal of Neuroinflammation |
| Acesso em linha: | http://www.jneuroinflammation.com/content/8/1/46 |
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