Llwytho...

STAT3, p38 MAPK, and NF-κB Drive Unopposed Monocyte-Dependent Fibroblast MMP-1 Secretion in Tuberculosis

Tissue destruction characterizes infection with Mycobacterium tuberculosis (Mtb). Type I collagen provides the lung's tensile strength, is extremely resistant to degradation, but is cleaved by matrix metalloproteinase (MMP)-1. Fibroblasts potentially secrete quantitatively more MMP-1 than other...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: O'Kane, Cecilia M., Elkington, Paul T., Jones, Michael D., Caviedes, Luz, Tovar, Marco, Gilman, Robert H., Stamp, Gordon, Friedland, Jon S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951877/
https://ncbi.nlm.nih.gov/pubmed/19915152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0211OC
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