Hypoxia and tissue destruction in pulmonary TB

BACKGROUND: It is unknown whether lesions in human TB are hypoxic or whether this influences disease pathology. Human TB is characterised by extensive lung destruction driven by host matrix metalloproteinases (MMPs), particularly collagenases such as matrix metalloproteinase-1 (MMP-1). METHODS: We i...

詳細記述

保存先:
書誌詳細
出版年:Thorax
主要な著者: Belton, Moerida, Brilha, Sara, Manavaki, Roido, Mauri, Francesco, Nijran, Kuldip, Hong, Young T, Patel, Neva H, Dembek, Marcin, Tezera, Liku, Green, Justin, Moores, Rachel, Aigbirhio, Franklin, Al-Nahhas, Adil, Fryer, Tim D, Elkington, Paul T, Friedland, Jon S
フォーマット: Artigo
言語:Inglês
出版事項: BMJ Publishing Group 2016
主題:
Tuberculosis
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5136721/
https://ncbi.nlm.nih.gov/pubmed/27245780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2015-207402
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