Epigenetic Regulation of Matrix Metalloproteinase-1 and -3 Expression in Mycobacterium tuberculosis Infection

In pulmonary tuberculosis (TB), the inflammatory immune response against Mycobacterium tuberculosis (Mtb) is associated with tissue destruction and cavitation, which drives disease transmission, chronic lung disease, and mortality. Matrix metalloproteinase (MMP)-1 is a host enzyme critical for the d...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Moores, Rachel C., Brilha, Sara, Schutgens, Frans, Elkington, Paul T., Friedland, Jon S.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442172/
https://ncbi.nlm.nih.gov/pubmed/28596772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00602
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