Epigenetic Regulation of Matrix Metalloproteinase-1 and -3 Expression in Mycobacterium tuberculosis Infection

In pulmonary tuberculosis (TB), the inflammatory immune response against Mycobacterium tuberculosis (Mtb) is associated with tissue destruction and cavitation, which drives disease transmission, chronic lung disease, and mortality. Matrix metalloproteinase (MMP)-1 is a host enzyme critical for the d...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Moores, Rachel C., Brilha, Sara, Schutgens, Frans, Elkington, Paul T., Friedland, Jon S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442172/
https://ncbi.nlm.nih.gov/pubmed/28596772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00602
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