Membrane Type 1 Matrix Metalloproteinase Regulates Monocyte Migration and Collagen Destruction in Tuberculosis

Tuberculosis (TB) remains a global pandemic and drug resistance is rising. Multicellular granuloma formation is the pathological hallmark of Mycobacterium tuberculosis infection. The membrane type 1 matrix metalloproteinase (MT1-MMP or MMP-14) is a collagenase that is key in leukocyte migration and...

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Vydáno v:J Immunol
Hlavní autoři: Sathyamoorthy, Tarangini, Tezera, Liku B., Walker, Naomi F., Brilha, Sara, Saraiva, Luisa, Mauri, Francesco A., Wilkinson, Robert J., Friedland, Jon S., Elkington, Paul T.
Médium: Artigo
Jazyk:Inglês
Vydáno: AAI 2015
Témata:
Clinical and Human Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505956/
https://ncbi.nlm.nih.gov/pubmed/26091717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403110
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