Preventing and exploiting the oncogenic potential of integrating gene vectors

od Modlich, Ute, Baum, Christopher
Izdano 2009

Efficiency and Safety of O(6)-Methylguanine DNA Methyltransferase (MGMT(P140K))-Mediated In Vivo Selection in a Humanized Mouse Model

od Phaltane, Ruhi, Haemmerle, Reinhard, Rothe, Michael, Modlich, Ute, Moritz, Thomas
Izdano 2014

Comparison of Different Cytokine Conditions Reveals Resveratrol as a New Molecule for Ex Vivo Cultivation of Cord Blood-Derived Hematopoietic Stem Cells

od Heinz, Niels, Ehrnström, Birgitta, Schambach, Axel, Schwarzer, Adrian, Modlich, Ute, Schiedlmeier, Bernhard
izdano v Stem Cells Transl Med (2015)

Clonal Dominance With Retroviral Vector Insertions Near the ANGPT1 and ANGPT2 Genes in a Human Xenotransplant Mouse Model

od Haemmerle, Reinhard, Phaltane, Ruhi, Rothe, Michael, Schröder, Simon, Schambach, Axel, Moritz, Thomas, Modlich, Ute
Izdano 2014

Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity

od Modlich, Ute, Bohne, Jens, Schmidt, Manfred, von Kalle, Christof, Knöss, Sabine, Schambach, Axel, Baum, Christopher
Izdano 2006

Gene therapy cures the anemia and lethal bone marrow failure in a mouse model of RPS19-deficient Diamond-Blackfan anemia

od Jaako, Pekka, Debnath, Shubhranshu, Olsson, Karin, Modlich, Ute, Rothe, Michael, Schambach, Axel, Flygare, Johan, Karlsson, Stefan
izdano v Haematologica (2014)

Evaluating a Ligation-Mediated PCR and Pyrosequencing Method for the Detection of Clonal Contribution in Polyclonal Retrovirally Transduced Samples

od Brugman, Martijn H., Suerth, Julia D., Rothe, Michael, Suerbaum, Sebastian, Schambach, Axel, Modlich, Ute, Kustikova, Olga, Baum, Christopher
Izdano 2013

Inhibition of Thrombopoietin/Mpl Signaling in Adult Hematopoiesis Identifies New Candidates for Hematopoietic Stem Cell Maintenance

od Kohlscheen, Saskia, Wintterle, Sabine, Schwarzer, Adrian, Kamp, Christel, Brugman, Martijn H., Breuer, Daniel C., Büsche, Guntram, Baum, Christopher, Modlich, Ute
izdano v PLoS One (2015)

Genotoxic Potential of Lineage-specific Lentivirus Vectors Carrying the β-Globin Locus Control Region

od Arumugam, Paritha I, Higashimoto, Tomoyasu, Urbinati, Fabrizia, Modlich, Ute, Nestheide, Shawna, Xia, Ping, Fox, Catherine, Corsinotti, Andrea, Baum, Christopher, Malik, Punam
Izdano 2009

Engineering Next-Generation BET-Independent MLV Vectors for Safer Gene Therapy

od El Ashkar, Sara, Van Looveren, Dominique, Schenk, Franziska, Vranckx, Lenard S., Demeulemeester, Jonas, De Rijck, Jan, Debyser, Zeger, Modlich, Ute, Gijsbers, Rik
izdano v Mol Ther Nucleic Acids (2017)

Gene Therapy of Mpl Deficiency: Challenging Balance Between Leukemia and Pancytopenia

od Wicke, Daniel C, Meyer, Johann, Buesche, Guntram, Heckl, Dirk, Kreipe, Hans, Li, Zhixiong, Welte, Karl H, Ballmaier, Matthias, Baum, Christopher, Modlich, Ute
Izdano 2009

Hematopoietic Stem Cell Transplantation Restores Naïve T-Cell Populations in Atm-Deficient Mice and in Preemptively Treated Patients With Ataxia-Telangiectasia

od Duecker, Ruth, Baer, Patrick C., Buecker, Aileen, Huenecke, Sabine, Pfeffermann, Lisa-Marie, Modlich, Ute, Bakhtiar, Shahrzad, Bader, Peter, Zielen, Stefan, Schubert, Ralf
izdano v Front Immunol (2019)

High Cytotoxic Efficiency of Lentivirally and Alpharetrovirally Engineered CD19-Specific Chimeric Antigen Receptor Natural Killer Cells Against Acute Lymphoblastic Leukemia

od Müller, Stephan, Bexte, Tobias, Gebel, Veronika, Kalensee, Franziska, Stolzenberg, Eva, Hartmann, Jessica, Koehl, Ulrike, Schambach, Axel, Wels, Winfried S., Modlich, Ute, Ullrich, Evelyn
izdano v Front Immunol (2020)

HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells

od Pilat, Sandra, Carotta, Sebastian, Schiedlmeier, Bernhard, Kamino, Kenji, Mairhofer, Andreas, Will, Elke, Modlich, Ute, Steinlein, Peter, Ostertag, Wolfram, Baum, Christopher, Beug, Hartmut, Klump, Hannes
Izdano 2005

Lentiviral Vector Induced Insertional Haploinsufficiency of Ebf1 Causes Murine Leukemia

od Heckl, Dirk, Schwarzer, Adrian, Haemmerle, Reinhard, Steinemann, Doris, Rudolph, Cornelia, Skawran, Britta, Knoess, Sabine, Krause, Johanna, Li, Zhixiong, Schlegelberger, Brigitte, Baum, Christopher, Modlich, Ute
Izdano 2012

Forming megakaryocytes from murine induced pluripotent stem cells by the inducible overexpression of supporting factors

od Cullmann, Katharina, Jahn, Magdalena, Spindler, Markus, Schenk, Franziska, Manukjan, Georgi, Mucci, Adele, Steinemann, Doris, Boller, Klaus, Schulze, Harald, Bender, Markus, Moritz, Thomas, Modlich, Ute
izdano v Res Pract Thromb Haemost (2020)

Insertional Transformation of Hematopoietic Cells by Self-inactivating Lentiviral and Gammaretroviral Vectors

od Modlich, Ute, Navarro, Susana, Zychlinski, Daniela, Maetzig, Tobias, Knoess, Sabine, Brugman, Martijn H., Schambach, Axel, Charrier, Sabine, Galy, Anne, Thrasher, Adrian J., Bueren, Juan, Baum, Christopher
Izdano 2009

Alpharetroviral Self-inactivating Vectors: Long-term Transgene Expression in Murine Hematopoietic Cells and Low Genotoxicity

od Suerth, Julia D, Maetzig, Tobias, Brugman, Martijn H, Heinz, Niels, Appelt, Jens-Uwe, Kaufmann, Kerstin B, Schmidt, Manfred, Grez, Manuel, Modlich, Ute, Baum, Christopher, Schambach, Axel
Izdano 2012

Lentiviral Gene Therapy Using Cellular Promoters Cures Type 1 Gaucher Disease in Mice

od Dahl, Maria, Doyle, Alexander, Olsson, Karin, Månsson, Jan-Eric, Marques, André R A, Mirzaian, Mina, Aerts, Johannes M, Ehinger, Mats, Rothe, Michael, Modlich, Ute, Schambach, Axel, Karlsson, Stefan
izdano v Mol Ther (2015)

In vivo generation of human CD19‐CAR T cells results in B‐cell depletion and signs of cytokine release syndrome

od Pfeiffer, Anett, Thalheimer, Frederic B, Hartmann, Sylvia, Frank, Annika M, Bender, Ruben R, Danisch, Simon, Costa, Caroline, Wels, Winfried S, Modlich, Ute, Stripecke, Renata, Verhoeyen, Els, Buchholz, Christian J
izdano v EMBO Mol Med (2018)