Preventing and exploiting the oncogenic potential of integrating gene vectors

Yazar: Modlich, Ute, Baum, Christopher
Baskı/Yayın Bilgisi 2009

Efficiency and Safety of O(6)-Methylguanine DNA Methyltransferase (MGMT(P140K))-Mediated In Vivo Selection in a Humanized Mouse Model

Yazar: Phaltane, Ruhi, Haemmerle, Reinhard, Rothe, Michael, Modlich, Ute, Moritz, Thomas
Baskı/Yayın Bilgisi 2014

Comparison of Different Cytokine Conditions Reveals Resveratrol as a New Molecule for Ex Vivo Cultivation of Cord Blood-Derived Hematopoietic Stem Cells

Yazar: Heinz, Niels, Ehrnström, Birgitta, Schambach, Axel, Schwarzer, Adrian, Modlich, Ute, Schiedlmeier, Bernhard
Yayımlandı Stem Cells Transl Med (2015)

Clonal Dominance With Retroviral Vector Insertions Near the ANGPT1 and ANGPT2 Genes in a Human Xenotransplant Mouse Model

Yazar: Haemmerle, Reinhard, Phaltane, Ruhi, Rothe, Michael, Schröder, Simon, Schambach, Axel, Moritz, Thomas, Modlich, Ute
Baskı/Yayın Bilgisi 2014

Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity

Yazar: Modlich, Ute, Bohne, Jens, Schmidt, Manfred, von Kalle, Christof, Knöss, Sabine, Schambach, Axel, Baum, Christopher
Baskı/Yayın Bilgisi 2006

Gene therapy cures the anemia and lethal bone marrow failure in a mouse model of RPS19-deficient Diamond-Blackfan anemia

Yazar: Jaako, Pekka, Debnath, Shubhranshu, Olsson, Karin, Modlich, Ute, Rothe, Michael, Schambach, Axel, Flygare, Johan, Karlsson, Stefan
Yayımlandı Haematologica (2014)

Evaluating a Ligation-Mediated PCR and Pyrosequencing Method for the Detection of Clonal Contribution in Polyclonal Retrovirally Transduced Samples

Yazar: Brugman, Martijn H., Suerth, Julia D., Rothe, Michael, Suerbaum, Sebastian, Schambach, Axel, Modlich, Ute, Kustikova, Olga, Baum, Christopher
Baskı/Yayın Bilgisi 2013

Inhibition of Thrombopoietin/Mpl Signaling in Adult Hematopoiesis Identifies New Candidates for Hematopoietic Stem Cell Maintenance

Yazar: Kohlscheen, Saskia, Wintterle, Sabine, Schwarzer, Adrian, Kamp, Christel, Brugman, Martijn H., Breuer, Daniel C., Büsche, Guntram, Baum, Christopher, Modlich, Ute
Yayımlandı PLoS One (2015)

Genotoxic Potential of Lineage-specific Lentivirus Vectors Carrying the β-Globin Locus Control Region

Yazar: Arumugam, Paritha I, Higashimoto, Tomoyasu, Urbinati, Fabrizia, Modlich, Ute, Nestheide, Shawna, Xia, Ping, Fox, Catherine, Corsinotti, Andrea, Baum, Christopher, Malik, Punam
Baskı/Yayın Bilgisi 2009

Engineering Next-Generation BET-Independent MLV Vectors for Safer Gene Therapy

Yazar: El Ashkar, Sara, Van Looveren, Dominique, Schenk, Franziska, Vranckx, Lenard S., Demeulemeester, Jonas, De Rijck, Jan, Debyser, Zeger, Modlich, Ute, Gijsbers, Rik
Yayımlandı Mol Ther Nucleic Acids (2017)

Gene Therapy of Mpl Deficiency: Challenging Balance Between Leukemia and Pancytopenia

Yazar: Wicke, Daniel C, Meyer, Johann, Buesche, Guntram, Heckl, Dirk, Kreipe, Hans, Li, Zhixiong, Welte, Karl H, Ballmaier, Matthias, Baum, Christopher, Modlich, Ute
Baskı/Yayın Bilgisi 2009

Hematopoietic Stem Cell Transplantation Restores Naïve T-Cell Populations in Atm-Deficient Mice and in Preemptively Treated Patients With Ataxia-Telangiectasia

Yazar: Duecker, Ruth, Baer, Patrick C., Buecker, Aileen, Huenecke, Sabine, Pfeffermann, Lisa-Marie, Modlich, Ute, Bakhtiar, Shahrzad, Bader, Peter, Zielen, Stefan, Schubert, Ralf
Yayımlandı Front Immunol (2019)

High Cytotoxic Efficiency of Lentivirally and Alpharetrovirally Engineered CD19-Specific Chimeric Antigen Receptor Natural Killer Cells Against Acute Lymphoblastic Leukemia

Yazar: Müller, Stephan, Bexte, Tobias, Gebel, Veronika, Kalensee, Franziska, Stolzenberg, Eva, Hartmann, Jessica, Koehl, Ulrike, Schambach, Axel, Wels, Winfried S., Modlich, Ute, Ullrich, Evelyn
Yayımlandı Front Immunol (2020)

HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells

Yazar: Pilat, Sandra, Carotta, Sebastian, Schiedlmeier, Bernhard, Kamino, Kenji, Mairhofer, Andreas, Will, Elke, Modlich, Ute, Steinlein, Peter, Ostertag, Wolfram, Baum, Christopher, Beug, Hartmut, Klump, Hannes
Baskı/Yayın Bilgisi 2005

Lentiviral Vector Induced Insertional Haploinsufficiency of Ebf1 Causes Murine Leukemia

Yazar: Heckl, Dirk, Schwarzer, Adrian, Haemmerle, Reinhard, Steinemann, Doris, Rudolph, Cornelia, Skawran, Britta, Knoess, Sabine, Krause, Johanna, Li, Zhixiong, Schlegelberger, Brigitte, Baum, Christopher, Modlich, Ute
Baskı/Yayın Bilgisi 2012

Forming megakaryocytes from murine induced pluripotent stem cells by the inducible overexpression of supporting factors

Yazar: Cullmann, Katharina, Jahn, Magdalena, Spindler, Markus, Schenk, Franziska, Manukjan, Georgi, Mucci, Adele, Steinemann, Doris, Boller, Klaus, Schulze, Harald, Bender, Markus, Moritz, Thomas, Modlich, Ute
Yayımlandı Res Pract Thromb Haemost (2020)

Insertional Transformation of Hematopoietic Cells by Self-inactivating Lentiviral and Gammaretroviral Vectors

Yazar: Modlich, Ute, Navarro, Susana, Zychlinski, Daniela, Maetzig, Tobias, Knoess, Sabine, Brugman, Martijn H., Schambach, Axel, Charrier, Sabine, Galy, Anne, Thrasher, Adrian J., Bueren, Juan, Baum, Christopher
Baskı/Yayın Bilgisi 2009

Alpharetroviral Self-inactivating Vectors: Long-term Transgene Expression in Murine Hematopoietic Cells and Low Genotoxicity

Yazar: Suerth, Julia D, Maetzig, Tobias, Brugman, Martijn H, Heinz, Niels, Appelt, Jens-Uwe, Kaufmann, Kerstin B, Schmidt, Manfred, Grez, Manuel, Modlich, Ute, Baum, Christopher, Schambach, Axel
Baskı/Yayın Bilgisi 2012

Lentiviral Gene Therapy Using Cellular Promoters Cures Type 1 Gaucher Disease in Mice

Yazar: Dahl, Maria, Doyle, Alexander, Olsson, Karin, Månsson, Jan-Eric, Marques, André R A, Mirzaian, Mina, Aerts, Johannes M, Ehinger, Mats, Rothe, Michael, Modlich, Ute, Schambach, Axel, Karlsson, Stefan
Yayımlandı Mol Ther (2015)

In vivo generation of human CD19‐CAR T cells results in B‐cell depletion and signs of cytokine release syndrome

Yazar: Pfeiffer, Anett, Thalheimer, Frederic B, Hartmann, Sylvia, Frank, Annika M, Bender, Ruben R, Danisch, Simon, Costa, Caroline, Wels, Winfried S, Modlich, Ute, Stripecke, Renata, Verhoeyen, Els, Buchholz, Christian J
Yayımlandı EMBO Mol Med (2018)