Targeting CD137 Enhances Vaccine-Elicited Anti-RSV CD8(+) T Cell Responses in Aged Mice

Por Lee, Sujin, Mittler, Robert S., Moore, Martin L.
Publicado em 2013

Hyper-costimulation Through 4-1BB Distorts Homeostasis of Immune cells

Por Lee, Seung-Woo, Salek-Ardakani, Shahram, Mittler, Robert S., Croft, Michael
Publicado em 2009

Effector CD8 T cells possess suppressor function after 4-1BB and Toll-like receptor triggering

Por Myers, Lara, Takahashi, Chikara, Mittler, Robert S., Rossi, Robert J., Vella, Anthony T.
Publicado em 2003

Anti–4-1bb Monoclonal Antibodies Abrogate T Cell–Dependent Humoral Immune Responses in Vivo through the Induction of Helper T Cell Anergy

Por Mittler, Robert S., Bailey, Tina S., Klussman, Kerry, Trailsmith, Mark D., Hoffmann, Michael K.
Publicado em 1999

The IKK-neutralizing compound Bay11 kills supereffector CD8 T cells by altering caspase-dependent activation-induced cell death

Por Lee, Seung-Joo, Long, Meixiao, Adler, Adam J., Mittler, Robert S., Vella, Anthony T.
Publicado em 2009

Adjuvantive effects of anti-4-1BB agonist Ab and 4-1BBL DNA for a HIV-1 Gag DNA vaccine: Different effects on cellular and humoral immunity

Por Ganguly, Sumita, Liu, Jinyan, Pillai, Vinod B., Mittler, Robert S., Amara, Rama Rao
Publicado em 2009

4-1BB and OX40 stimulation enhance CD8 and CD4 T-cell responses to a DNA prime, poxvirus boost vaccine

Por Munks, Michael W, Mourich, Dan V, Mittler, Robert S, Weinberg, Andrew D, Hill, Ann B
Publicado em 2004

Identification of Regulatory Functions for 4-1BB and 4-1BBL in Myelopoiesis and the Development of Dendritic Cells

Por Lee, Seung-Woo, Park, Yunji, So, Takanori, Kwon, Byoung S., Cheroutre, Hilde, Mittler, Robert S., Croft, Michael
Publicado em 2008

CD137-mediated immunotherapy for chronic viral infection

Por Robertson, Shelly J., Messer, Ronald J., Carmody, Aaron B., Mittler, Robert S., Burlak, Christopher, Hasenkrug, Kim J.
Publicado em 2008

CD137-mediated immunotherapy for allergic asthma

Por Polte, Tobias, Foell, Juergen, Werner, Christoph, Hoymann, Heinz-Gerd, Braun, Armin, Burdach, Stefan, Mittler, Robert S., Hansen, Gesine
Publicado em 2006

Multivalent 4-1BB binding aptamers costimulate CD8(+) T cells and inhibit tumor growth in mice

Por McNamara, James O., Kolonias, Despina, Pastor, Fernando, Mittler, Robert S., Chen, Lieping, Giangrande, Paloma H., Sullenger, Bruce, Gilboa, Eli
Publicado em 2007

The B10 Idd9.3 locus mediates accumulation of functionally superior CD137(pos) T regulatory cells in the NOD Type 1 diabetes model

Por Kachapati, Kritika, Adams, David E., Wu, Yuehong, Steward, Charles A., Rainbow, Daniel B., Wicker, Linda S., Mittler, Robert S., Ridgway, William M.
Publicado em 2012

4-1BB (CD137) Differentially Regulates Murine In Vivo Protein- and Polysaccharide-Specific Immunoglobulin Isotype Responses to Streptococcus pneumoniae

Por Wu, Zheng-Qi, Khan, Abdul Q., Shen, Yi, Wolcott, Karen M., Dawicki, Wojciech, Watts, Tania H., Mittler, Robert S., Snapper, Clifford M.
Publicado em 2003

4-1BB Signaling Synergizes with Programmed Death Ligand 1 Blockade To Augment CD8 T Cell Responses during Chronic Viral Infection

Por Vezys, Vaiva, Penaloza-MacMaster, Pablo, Barber, Daniel L., Ha, Sang-Jun, Konieczny, Bogumila, Freeman, Gordon J., Mittler, Robert S., Ahmed, Rafi
Publicado no J Immunol (2011)

Antigen-Specific CD4(+) T Cells Recognize Epitopes of Protective Antigen following Vaccination with an Anthrax Vaccine

Por Laughlin, Elsa M., Miller, Joseph D., James, Eddie, Fillos, Dimitri, Ibegbu, Chris C., Mittler, Robert S., Akondy, Rama, Kwok, William, Ahmed, Rafi, Nepom, Gerald
Publicado em 2007

Antigen-Specific CD4(+) T Cells Recognize Epitopes of Protective Antigen following Vaccination with an Anthrax Vaccine

Por Laughlin, Elsa M., Miller, Joseph D., James, Eddie, Fillos, Dimitri, Ibegbu, Chris C., Mittler, Robert S., Akondy, Rama, Kwok, William, Ahmed, Rafi, Nepom, Gerald
Publicado em 2007

Immune suppression or enhancement by CD137 T cell costimulation during acute viral infection is time dependent

Por Zhang, Benyue, Maris, Charles H., Foell, Juergen, Whitmire, Jason, Niu, Liguo, Song, Jing, Kwon, Byoung S., Vella, Anthony T., Ahmed, Rafi, Jacob, Joshy, Mittler, Robert S.
Publicado em 2007

Engagement of the CD137 (4-1BB) costimulatory molecule inhibits and reverses the autoimmune process in collagen-induced arthritis and establishes lasting disease resistance

Por Foell, Juergen L, Diez-Mendiondo, Belkis I, Diez, Oliver H, Holzer, Ursula, Ruck, Peter, Bapat, Abhijit S, Hoffmann, Michael K, Mittler, Robert S, Dannecker, Guenther E
Publicado em 2004

Cytokine-Mediated Disruption of Lymphocyte Trafficking, Hemopoiesis, and Induction of Lymphopenia, Anemia, and Thrombocytopenia in Anti-CD137-Treated Mice

Por Niu, Liguo, Strahotin, Simona, Hewes, Becker, Zhang, Benyue, Zhang, Yuanyuan, Archer, David, Spencer, Trent, Dillehay, Dirck, Kwon, Byoung, Chen, Lieping, Vella, Anthony T., Mittler, Robert S.
Publicado em 2007

Self-Antigen Prevents CD8 T Cell Effector Differentiation by CD134 and CD137 Dual Costimulation

Por Bandyopadhyay, Suman, Long, Meixiao, Qui, Harry Z., Hagymasi, Adam T., Slaiby, Aaron M., Mihalyo, Marianne A., Aguila, Hector L., Mittler, Robert S., Vella, Anthony T., Adler, Adam J.
Publicado em 2008