Targeting CD137 Enhances Vaccine-Elicited Anti-RSV CD8(+) T Cell Responses in Aged Mice

по Lee, Sujin, Mittler, Robert S., Moore, Martin L.
Опубликовано 2013

Hyper-costimulation Through 4-1BB Distorts Homeostasis of Immune cells

по Lee, Seung-Woo, Salek-Ardakani, Shahram, Mittler, Robert S., Croft, Michael
Опубликовано 2009

Effector CD8 T cells possess suppressor function after 4-1BB and Toll-like receptor triggering

по Myers, Lara, Takahashi, Chikara, Mittler, Robert S., Rossi, Robert J., Vella, Anthony T.
Опубликовано 2003

Anti–4-1bb Monoclonal Antibodies Abrogate T Cell–Dependent Humoral Immune Responses in Vivo through the Induction of Helper T Cell Anergy

по Mittler, Robert S., Bailey, Tina S., Klussman, Kerry, Trailsmith, Mark D., Hoffmann, Michael K.
Опубликовано 1999

The IKK-neutralizing compound Bay11 kills supereffector CD8 T cells by altering caspase-dependent activation-induced cell death

по Lee, Seung-Joo, Long, Meixiao, Adler, Adam J., Mittler, Robert S., Vella, Anthony T.
Опубликовано 2009

Adjuvantive effects of anti-4-1BB agonist Ab and 4-1BBL DNA for a HIV-1 Gag DNA vaccine: Different effects on cellular and humoral immunity

по Ganguly, Sumita, Liu, Jinyan, Pillai, Vinod B., Mittler, Robert S., Amara, Rama Rao
Опубликовано 2009

4-1BB and OX40 stimulation enhance CD8 and CD4 T-cell responses to a DNA prime, poxvirus boost vaccine

по Munks, Michael W, Mourich, Dan V, Mittler, Robert S, Weinberg, Andrew D, Hill, Ann B
Опубликовано 2004

Identification of Regulatory Functions for 4-1BB and 4-1BBL in Myelopoiesis and the Development of Dendritic Cells

по Lee, Seung-Woo, Park, Yunji, So, Takanori, Kwon, Byoung S., Cheroutre, Hilde, Mittler, Robert S., Croft, Michael
Опубликовано 2008

CD137-mediated immunotherapy for chronic viral infection

по Robertson, Shelly J., Messer, Ronald J., Carmody, Aaron B., Mittler, Robert S., Burlak, Christopher, Hasenkrug, Kim J.
Опубликовано 2008

CD137-mediated immunotherapy for allergic asthma

по Polte, Tobias, Foell, Juergen, Werner, Christoph, Hoymann, Heinz-Gerd, Braun, Armin, Burdach, Stefan, Mittler, Robert S., Hansen, Gesine
Опубликовано 2006

Multivalent 4-1BB binding aptamers costimulate CD8(+) T cells and inhibit tumor growth in mice

по McNamara, James O., Kolonias, Despina, Pastor, Fernando, Mittler, Robert S., Chen, Lieping, Giangrande, Paloma H., Sullenger, Bruce, Gilboa, Eli
Опубликовано 2007

The B10 Idd9.3 locus mediates accumulation of functionally superior CD137(pos) T regulatory cells in the NOD Type 1 diabetes model

по Kachapati, Kritika, Adams, David E., Wu, Yuehong, Steward, Charles A., Rainbow, Daniel B., Wicker, Linda S., Mittler, Robert S., Ridgway, William M.
Опубликовано 2012

4-1BB (CD137) Differentially Regulates Murine In Vivo Protein- and Polysaccharide-Specific Immunoglobulin Isotype Responses to Streptococcus pneumoniae

по Wu, Zheng-Qi, Khan, Abdul Q., Shen, Yi, Wolcott, Karen M., Dawicki, Wojciech, Watts, Tania H., Mittler, Robert S., Snapper, Clifford M.
Опубликовано 2003

4-1BB Signaling Synergizes with Programmed Death Ligand 1 Blockade To Augment CD8 T Cell Responses during Chronic Viral Infection

по Vezys, Vaiva, Penaloza-MacMaster, Pablo, Barber, Daniel L., Ha, Sang-Jun, Konieczny, Bogumila, Freeman, Gordon J., Mittler, Robert S., Ahmed, Rafi
Опубликовано в: J Immunol (2011)

Antigen-Specific CD4(+) T Cells Recognize Epitopes of Protective Antigen following Vaccination with an Anthrax Vaccine

по Laughlin, Elsa M., Miller, Joseph D., James, Eddie, Fillos, Dimitri, Ibegbu, Chris C., Mittler, Robert S., Akondy, Rama, Kwok, William, Ahmed, Rafi, Nepom, Gerald
Опубликовано 2007

Antigen-Specific CD4(+) T Cells Recognize Epitopes of Protective Antigen following Vaccination with an Anthrax Vaccine

по Laughlin, Elsa M., Miller, Joseph D., James, Eddie, Fillos, Dimitri, Ibegbu, Chris C., Mittler, Robert S., Akondy, Rama, Kwok, William, Ahmed, Rafi, Nepom, Gerald
Опубликовано 2007

Immune suppression or enhancement by CD137 T cell costimulation during acute viral infection is time dependent

по Zhang, Benyue, Maris, Charles H., Foell, Juergen, Whitmire, Jason, Niu, Liguo, Song, Jing, Kwon, Byoung S., Vella, Anthony T., Ahmed, Rafi, Jacob, Joshy, Mittler, Robert S.
Опубликовано 2007

Engagement of the CD137 (4-1BB) costimulatory molecule inhibits and reverses the autoimmune process in collagen-induced arthritis and establishes lasting disease resistance

по Foell, Juergen L, Diez-Mendiondo, Belkis I, Diez, Oliver H, Holzer, Ursula, Ruck, Peter, Bapat, Abhijit S, Hoffmann, Michael K, Mittler, Robert S, Dannecker, Guenther E
Опубликовано 2004

Cytokine-Mediated Disruption of Lymphocyte Trafficking, Hemopoiesis, and Induction of Lymphopenia, Anemia, and Thrombocytopenia in Anti-CD137-Treated Mice

по Niu, Liguo, Strahotin, Simona, Hewes, Becker, Zhang, Benyue, Zhang, Yuanyuan, Archer, David, Spencer, Trent, Dillehay, Dirck, Kwon, Byoung, Chen, Lieping, Vella, Anthony T., Mittler, Robert S.
Опубликовано 2007

Self-Antigen Prevents CD8 T Cell Effector Differentiation by CD134 and CD137 Dual Costimulation

по Bandyopadhyay, Suman, Long, Meixiao, Qui, Harry Z., Hagymasi, Adam T., Slaiby, Aaron M., Mihalyo, Marianne A., Aguila, Hector L., Mittler, Robert S., Vella, Anthony T., Adler, Adam J.
Опубликовано 2008