Biological diversity and risk-adapted treatment of chronic lymphocytic leukemia

Por Zenz, Thorsten, Mertens, Daniel, Stilgenbauer, Stephan
Publicado em 2010

Chronic lymphocytic leukemia – genomics lead the way

Por Mertens, Daniel, Bullinger, Lars, Stilgenbauer, Stephan
Publicado em 2011

Advances in treating chronic lymphocytic leukemia

Por Tausch, Eugen, Mertens, Daniel, Stilgenbauer, Stephan
Publicado em 2014

TCL1A and ATM are co-expressed in chronic lymphocytic leukemia cells without deletion of 11q

Por Garding, Angela, Bhattacharya, Nupur, Haebe, Sarah, Müller, Frederike, Weichenhan, Dieter, Idler, Irina, Ickstadt, Katja, Stilgenbauer, Stephan, Mertens, Daniel
Publicado em 2013

Off-target effects of siRNA specific for GFP

Por Tschuch, Cordula, Schulz, Angela, Pscherer, Armin, Werft, Wiebke, Benner, Axel, Hotz-Wagenblatt, Agnes, Barrionuevo, Leticia Serra, Lichter, Peter, Mertens, Daniel
Publicado em 2008

The Phospholipase Cγ(2) Mutants R665W and L845F Identified in Ibrutinib-resistant Chronic Lymphocytic Leukemia Patients Are Hypersensitive to the Rho GTPase Rac2 Protein

Por Walliser, Claudia, Hermkes, Elisabeth, Schade, Anja, Wiese, Sebastian, Deinzer, Julia, Zapatka, Marc, Désiré, Laurent, Mertens, Daniel, Stilgenbauer, Stephan, Gierschik, Peter
Publicado no J Biol Chem (2016)

Programmed Death-1 and Its Ligand Are Novel Immunotolerant Molecules Expressed on Leukemic B Cells in Chronic Lymphocytic Leukemia

Por Grzywnowicz, Maciej, Zaleska, Joanna, Mertens, Daniel, Tomczak, Waldemar, Wlasiuk, Paulina, Kosior, Kamila, Piechnik, Agnieszka, Bojarska-Junak, Agnieszka, Dmoszynska, Anna, Giannopoulos, Krzysztof
Publicado em 2012

Allelic silencing at the tumor-suppressor locus 13q14.3 suggests an epigenetic tumor-suppressor mechanism

Por Mertens, Daniel, Wolf, Stephan, Tschuch, Cordula, Mund, Cora, Kienle, Dirk, Ohl, Sibylle, Schroeter, Petra, Lyko, Frank, Döhner, Hartmut, Stilgenbauer, Stephan, Lichter, Peter
Publicado em 2006

Krüppel-like factor 4 (KLF4) inactivation in chronic lymphocytic leukemia correlates with promoter DNA-methylation and can be reversed by inhibition of NOTCH signaling

Por Filarsky, Katharina, Garding, Angela, Becker, Natalia, Wolf, Christine, Zucknick, Manuela, Claus, Rainer, Weichenhan, Dieter, Plass, Christoph, Döhner, Hartmut, Stilgenbauer, Stephan, Lichter, Peter, Mertens, Daniel
Publicado no Haematologica (2016)

Germline Allele-Specific Expression of DAPK1 in Chronic Lymphocytic Leukemia

Por Wei, Quan-Xiang, Claus, Rainer, Hielscher, Thomas, Mertens, Daniel, Raval, Aparna, Oakes, Christopher C., Tanner, Stephan M., de la Chapelle, Albert, Byrd, John C., Stilgenbauer, Stephan, Plass, Christoph
Publicado em 2013

Protein expression analysis of chronic lymphocytic leukemia defines the effect of genetic aberrations and uncovers a correlation of CDK4, P27 and P53 with hierarchical risk

Por Winkler, Dirk, Schneider, Christof, Zucknick, Manuela, Bögelein, Daniela, Schulze, Kerstin, Zenz, Thorsten, Mohr, Julia, Philippen, Angela, Huber, Henriette, Bühler, Andreas, Habermann, Annett, Benner, Axel, Döhner, Hartmut, Stilgenbauer, Stephan, Mertens, Daniel
Publicado em 2010

Matrix-Dependent Regulation of AKT in Hepsin-Overexpressing PC3 Prostate Cancer Cells

Por Wittig-Blaich, Stephanie M, Kacprzyk, Lukasz A, Eismann, Thorsten, Bewerunge-Hudler, Melanie, Kruse, Petra, Winkler, Eva, Strauss, Wolfgang S L, Hibst, Raimund, Steiner, Rudolf, Schrader, Mark, Mertens, Daniel, Sültmann, Holger, Wittig, Rainer
Publicado em 2011

CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling

Por Faber, Katrin, Bullinger, Lars, Ragu, Christine, Garding, Angela, Mertens, Daniel, Miller, Christina, Martin, Daniela, Walcher, Daniel, Döhner, Konstanze, Döhner, Hartmut, Claus, Rainer, Plass, Christoph, Sykes, Stephen M., Lane, Steven W., Scholl, Claudia, Fröhling, Stefan
Publicado em 2012

Evolution of DNA Methylation Is Linked to Genetic Aberrations in Chronic Lymphocytic Leukemia

Por Oakes, Christopher C., Claus, Rainer, Gu, Lei, Assenov, Yassen, Hüllein, Jennifer, Zucknick, Manuela, Bieg, Matthias, Brocks, David, Bogatyrova, Olga, Schmidt, Christopher R., Rassenti, Laura, Kipps, Thomas J., Mertens, Daniel, Lichter, Peter, Döhner, Hartmut, Stilgenbauer, Stephan, Byrd, John C., Zenz, Thorsten, Plass, Christoph
Publicado em 2013

Quantitative DNA Methylation Analysis Identifies a Single CpG Dinucleotide Important for ZAP-70 Expression and Predictive of Prognosis in Chronic Lymphocytic Leukemia

Por Claus, Rainer, Lucas, David M., Stilgenbauer, Stephan, Ruppert, Amy S., Yu, Lianbo, Zucknick, Manuela, Mertens, Daniel, Bühler, Andreas, Oakes, Christopher C., Larson, Richard A., Kay, Neil E., Jelinek, Diane F., Kipps, Thomas J., Rassenti, Laura Z., Gribben, John G., Döhner, Hartmut, Heerema, Nyla A., Marcucci, Guido, Plass, Christoph, Byrd, John C.
Publicado em 2012

Epigenetic Upregulation of lncRNAs at 13q14.3 in Leukemia Is Linked to the In Cis Downregulation of a Gene Cluster That Targets NF-kB

Por Garding, Angela, Bhattacharya, Nupur, Claus, Rainer, Ruppel, Melanie, Tschuch, Cordula, Filarsky, Katharina, Idler, Irina, Zucknick, Manuela, Caudron-Herger, Maïwen, Oakes, Christopher, Fleig, Verena, Keklikoglou, Ioanna, Allegra, Danilo, Serra, Leticia, Thakurela, Sudhir, Tiwari, Vijay, Weichenhan, Dieter, Benner, Axel, Radlwimmer, Bernhard, Zentgraf, Hanswalter, Wiemann, Stefan, Rippe, Karsten, Plass, Christoph, Döhner, Hartmut, Lichter, Peter, Stilgenbauer, Stephan, Mertens, Daniel
Publicado em 2013

DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia

Por Oakes, Christopher C, Seifert, Marc, Assenov, Yassen, Gu, Lei, Przekopowitz, Martina, Ruppert, Amy S, Wang, Qi, Imbusch, Charles D, Serva, Andrius, Koser, Sandra D, Brocks, David, Lipka, Daniel B, Bogatyrova, Olga, Weichenhan, Dieter, Brors, Benedikt, Rassenti, Laura, Kipps, Thomas J, Mertens, Daniel, Zapatka, Marc, Lichter, Peter, Döhner, Hartmut, Küppers, Ralf, Zenz, Thorsten, Stilgenbauer, Stephan, Byrd, John C, Plass, Christoph
Publicado no Nat Genet (2016)

Mutations driving CLL and their evolution in progression and relapse

Por Landau, Dan A., Tausch, Eugen, Taylor-Weiner, Amaro N, Stewart, Chip, Reiter, Johannes G., Bahlo, Jasmin, Kluth, Sandra, Bozic, Ivana, Lawrence, Mike, Böttcher, Sebastian, Carter, Scott L., Cibulskis, Kristian, Mertens, Daniel, Sougnez, Carrie, Rosenberg, Mara, Hess, Julian M., Edelmann, Jennifer, Kless, Sabrina, Kneba, Michael, Ritgen, Matthias, Fink, Anna, Fischer, Kirsten, Gabriel, Stacey, Lander, Eric, Nowak, Martin A., Döhner, Hartmut, Hallek, Michael, Neuberg, Donna, Getz, Gad, Stilgenbauer, Stephan, Wu, Catherine J.
Publicado no Nature (2015)