The clonal composition of human CD4+CD25+Foxp3+ cells determined by a comprehensive DNA-based multiplex PCR for TCRB gene rearrangements

Por Scheinberg, Phillip, Melenhorst, Jan J., Hill, Brenna J., Keyvanfar, Keyvan, Barrett, A. John, Price, David A., Douek, Daniel C.
Publicado no J Immunol Methods (2007)

Donor lymphocyte count and thymic activity predict lymphocyte recovery and outcomes after matched-sibling hematopoietic stem cell transplant

Por McIver, Zachariah, Melenhorst, Jan Joseph, Wu, Colin, Grim, Andrew, Ito, Sawa, Cho, Irene, Hensel, Nancy, Battiwalla, Minoo, Barrett, Austin John
Publicado em 2013

Measuring IL-6 and sIL-6R in serum from patients treated with tocilizumab and/or siltuximab following CAR T cell therapy

Por Chen, Fang, Teachey, David T., Pequignot, Edward, Frey, Noelle, Porter, David, Maude, Shannon L., Grupp, Stephan A., June, Carl H., Melenhorst, Jan J., Lacey, Simon F.
Publicado no J Immunol Methods (2016)

KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice

Por Zhao, Ling, Melenhorst, Jan J., Alemu, Lemlem, Kirby, Martha, Anderson, Stacie, Kench, Maggie, Hoogstraten-Miller, Shelley, Brinster, Lauren, Kamikubo, Yasuhiko, Gilliland, D. Gary, Liu, P. Paul
Publicado em 2012

Timing and intensity of exposure to interferon-γ critically determines the function of monocyte-derived dendritic cells

Por Kerkar, Sid P, Chinnasamy, Dhanalakshmi, Hadi, Neima, Melenhorst, Jan, Muranski, Pawel, Spyridonidis, Alexandros, Ito, Sawa, Weber, Gerrit, Yin, Fang, Hensel, Nancy, Wang, Ena, Marincola, Francesco M, Barrett, Austin John
Publicado em 2014

The transfer of adaptive immunity to CMV during hematopoietic stem cell transplantation is dependent on the specificity and phenotype of CMV-specific T cells in the donor

Por Scheinberg, Phillip, Melenhorst, Jan J., Brenchley, Jason M., Hill, Brenna J., Hensel, Nancy F., Chattopadhyay, Pratip K., Roederer, Mario, Picker, Louis J., Price, David A., Barrett, A. John, Douek, Daniel C.
Publicado em 2009

Graft Versus Leukemia Response Without Graft-versus-host Disease Elicited By Adoptively Transferred Multivirus-specific T-cells

Por Melenhorst, Jan J, Castillo, Paul, Hanley, Patrick J, Keller, Michael D, Krance, Robert A, Margolin, Judith, Leen, Ann M, Heslop, Helen E, Barrett, A John, Rooney, Cliona M, Bollard, Catherine M
Publicado no Mol Ther (2015)

Cytopenia and leukocyte recovery shape cytokine fluctuations after myeloablative allogeneic hematopoietic stem cell transplantation

Por Melenhorst, Jan Joseph, Tian, Xin, Xu, Dihua, Sandler, Netanya G., Scheinberg, Philip, Biancotto, Angelique, Scheinberg, Priscila, McCoy, John Phil, Hensel, Nancy F., McIver, Zach, Douek, Daniel C, Barrett, Austin John
Publicado em 2012

Bone marrow mesenchymal stromal cells to treat tissue damage in allogeneic stem cell transplant recipients: Correlation of biological markers with clinical responses

Por Yin, Fang, Battiwalla, Minoo, Ito, Sawa, Feng, Xingmin, Chinian, Fariba, Melenhorst, Jan Joseph, Koklanaris, Eleftheria, Sabatino, Marianna, Stroncek, David, Samsel, Leigh, Klotz, Jeffrey, Hensel, Nancy F., Robey, Pamela G., Barrett, A. John
Publicado em 2014

Treatment of leukemia antigen-loss relapses occurring after CD19-targeted immunotherapies by combination of anti-CD123 and anti-CD19 chimeric antigen receptor T cells

Por Ruella, Marco, Barrett, David M, Kenderian, Saad S, Shestova, Olga, Hofmann, Ted J, Scholler, John, Lacey, Simon F, Melenhorst, Jan J, Nazimuddin, Farzana, Perazzelli, Jessica, Christian, David A, Hunter, Christopher A, Porter, David L, June, Carl H, Grupp, Stephan A, Gill, Saar
Publicado no J Immunother Cancer (2015)

IMCT-15 PILOT STUDY OF T CELLS REDIRECTED TO EGFRvIII WITH A CHIMERIC ANTIGEN RECEPTOR IN PATIENTS WITH EGFRvIII+ GLIOBLASTOMA

Por O'Rourke, Donald, Desai, Arati, Morrissette, Jennifer, Martinez-Lage, Maria, Nasrallah, MacLean, Brem, Steven, Maloney, Eileen, Shen, Angela, Mohan, Suyash, Wang, Sumei, Verma, Gaurav, Lacey, Simon, Melenhorst, Jan, Navenot, Jean-Marc, Zheng, Zhaohui, Levine, Bruce, Okada, Hideho, June, Carl, Maus, Marcela
Publicado no Neuro Oncol (2015)

Ultra-low Dose Interleukin-2 Promotes Immune-modulating Function of Regulatory T Cells and Natural Killer Cells in Healthy Volunteers

Por Ito, Sawa, Bollard, Catherine M, Carlsten, Mattias, Melenhorst, Jan Joseph, Biancotto, Angélique, Wang, Ena, Chen, Jinguo, Kotliarov, Yuri, Cheung, Foo, Xie, Zhi, Marincola, Francesco, Tanimoto, Kazushi, Battiwalla, Minoo, Olnes, Matthew J, Perl, Shira, Schum, Paula, Hughes, Thomas E, Keyvanfar, Keyvan, Hensel, Nancy, Muranski, Pawel, Young, Neal S, Barrett, A John
Publicado em 2014

CMV-Specific T-cells Generated From Naïve T-cells Recognize Atypical Epitopes And May Be Protective in Vivo

Por Hanley, Patrick J., Melenhorst, Jan J., Nikiforow, Sarah, Scheinberg, Phillip, Blaney, James W., Demmler-Harrison, Gail, Cruz, C. Russell, Lam, Sharon, Krance, Robert A., Leung, Kathryn S., Martinez, Caridad A., Liu, Hao, Heslop, Helen E., Rooney, Cliona M., Shpall, Elizabeth J., Barrett, A. John, Rodgers, John R., Bollard, Catherine M.
Publicado no Sci Transl Med (2015)

Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia

Por Maude, Shannon L., Frey, Noelle, Shaw, Pamela A., Aplenc, Richard, Barrett, David M., Bunin, Nancy J., Chew, Anne, Gonzalez, Vanessa E., Zheng, Zhaohui, Lacey, Simon F., Mahnke, Yolanda D., Melenhorst, Jan J., Rheingold, Susan R., Shen, Angela, Teachey, David T., Levine, Bruce L., June, Carl H., Porter, David L., Grupp, Stephan A.
Publicado no N Engl J Med (2014)

Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapy

Por Bhoj, Vijay G., Arhontoulis, Dimitrios, Wertheim, Gerald, Capobianchi, James, Callahan, Colleen A., Ellebrecht, Christoph T., Obstfeld, Amrom E., Lacey, Simon F., Melenhorst, Jan J., Nazimuddin, Farzana, Hwang, Wei-Ting, Maude, Shannon L., Wasik, Mariusz A., Bagg, Adam, Schuster, Stephen, Feldman, Michael D., Porter, David L., Grupp, Stephen A., June, Carl H., Milone, Michael C.
Publicado no Blood (2016)

Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies

Por Ruella, Marco, Barrett, David M., Kenderian, Saad S., Shestova, Olga, Hofmann, Ted J., Perazzelli, Jessica, Klichinsky, Michael, Aikawa, Vania, Nazimuddin, Farzana, Kozlowski, Miroslaw, Scholler, John, Lacey, Simon F., Melenhorst, Jan J., Morrissette, Jennifer J.D., Christian, David A., Hunter, Christopher A., Kalos, Michael, Porter, David L., June, Carl H., Grupp, Stephan A., Gill, Saar
Publicado no J Clin Invest (2016)

Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy

Por Sotillo, Elena, Barrett, David M., Black, Kathryn L, Bagashev, Asen, Oldridge, Derek, Wu, Glendon, Sussman, Robyn, Lanauze, Claudia, Ruella, Marco, Gazzara, Matthew R., Martinez, Nicole M., Harrington, Colleen T., Chung, Elaine Y., Perazzelli, Jessica, Hofmann, Ted J., Maude, Shannon L., Raman, Pichai, Barrera, Alejandro, Gill, Saar, Lacey, Simon F., Melenhorst, Jan J., Allman, David, Jacoby, Elad, Fry, Terry, Mackall, Crystal, Barash, Yoseph, Lynch, Kristen W., Maris, John M., Grupp, Stephan A., Thomas-Tikhonenko, Andrei
Publicado no Cancer Discov (2015)

Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia

Por Fraietta, Joseph A., Beckwith, Kyle A., Patel, Prachi R., Ruella, Marco, Zheng, Zhaohui, Barrett, David M., Lacey, Simon F., Melenhorst, Jan Joseph, McGettigan, Shannon E., Cook, Danielle R., Zhang, Changfeng, Xu, Jun, Do, Priscilla, Hulitt, Jessica, Kudchodkar, Sagar B., Cogdill, Alexandria P., Gill, Saar, Porter, David L., Woyach, Jennifer A., Long, Meixiao, Johnson, Amy J., Maddocks, Kami, Muthusamy, Natarajan, Levine, Bruce L., June, Carl H., Byrd, John C., Maus, Marcela V.
Publicado no Blood (2016)