CMV-Specific T-cells Generated From Naïve T-cells Recognize Atypical Epitopes And May Be Protective in Vivo

Adoptive transfer of adult-seropositive, cytomegalovirus (CMV)-specific T-cells can effectively restore antiviral immunity after transplantation. Lack of CMV-specific memory T-cells in blood from CMV-seronegative adult and cord blood (CB) donors restricts the availability of donor-derived virus-spec...

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Publié dans:Sci Transl Med
Auteurs principaux: Hanley, Patrick J., Melenhorst, Jan J., Nikiforow, Sarah, Scheinberg, Phillip, Blaney, James W., Demmler-Harrison, Gail, Cruz, C. Russell, Lam, Sharon, Krance, Robert A., Leung, Kathryn S., Martinez, Caridad A., Liu, Hao, Heslop, Helen E., Rooney, Cliona M., Shpall, Elizabeth J., Barrett, A. John, Rodgers, John R., Bollard, Catherine M.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479400/
https://ncbi.nlm.nih.gov/pubmed/25925682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa2546
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