Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes

The naive phenotype of cord blood (CB) T cells may reduce graft-versus-host disease after umbilical cord blood transplantation, but this naivety and their low absolute numbers also delays immune reconstitution, producing higher infection-related mortality that is predominantly related to CMV, adenov...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Hanley, Patrick J., Cruz, Conrad Russell Young, Savoldo, Barbara, Leen, Ann M., Stanojevic, Maja, Khalil, Mariam, Decker, William, Molldrem, Jeffrey J., Liu, Hao, Gee, Adrian P., Rooney, Cliona M., Heslop, Helen E., Dotti, Gianpietro, Brenner, Malcolm K., Shpall, Elizabeth J., Bollard, Catherine M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2009
Schlagworte:
Transplantation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738578/
https://ncbi.nlm.nih.gov/pubmed/19443656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-213256
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge