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Cytotoxic T Lymphocytes Simultaneously Targeting Multiple Tumor-associated Antigens to Treat EBV Negative Lymphoma

Although immunotherapy with Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes (CTLs) can treat EBV-associated Hodgkin and non-Hodgkin lymphoma (HL/NHL), more than 50% of such tumors are EBV negative. We now describe an approach that allows us to consistently generate, in a single line, CTLs...

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Hlavní autoři: Gerdemann, Ulrike, Katari, Usha, Christin, Anne S, Cruz, Conrad R, Tripic, Tamara, Rousseau, Alexandra, Gottschalk, Stephen M, Savoldo, Barbara, Vera, Juan F, Heslop, Helen E, Brenner, Malcolm K, Bollard, Catherine M, Rooney, Cliona M, Leen, Ann M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242656/
https://ncbi.nlm.nih.gov/pubmed/21915103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.167
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