Cytotoxic T Lymphocytes Simultaneously Targeting Multiple Tumor-associated Antigens to Treat EBV Negative Lymphoma

Although immunotherapy with Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes (CTLs) can treat EBV-associated Hodgkin and non-Hodgkin lymphoma (HL/NHL), more than 50% of such tumors are EBV negative. We now describe an approach that allows us to consistently generate, in a single line, CTLs...

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Detalhes bibliográficos
Main Authors: Gerdemann, Ulrike, Katari, Usha, Christin, Anne S, Cruz, Conrad R, Tripic, Tamara, Rousseau, Alexandra, Gottschalk, Stephen M, Savoldo, Barbara, Vera, Juan F, Heslop, Helen E, Brenner, Malcolm K, Bollard, Catherine M, Rooney, Cliona M, Leen, Ann M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242656/
https://ncbi.nlm.nih.gov/pubmed/21915103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.167
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