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Safety and clinical efficacy of rapidly-generated trivirus-directed T cells as treatment for adenovirus, EBV, and CMV infections after allogeneic hematopoietic stem cell transplant

Adoptive transfer of virus-specific T cells can prevent and treat serious infections with Epstein-Barr virus (EBV), cytomegalovirus (CMV), and adenovirus (Adv) after allogeneic hematopoietic stem cell transplant. It has, however, proved difficult to make this approach widely available since infectio...

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Detalhes bibliográficos
Main Authors: Gerdemann, Ulrike, Katari, Usha L, Papadopoulou, Anastasia, Keirnan, Jacqueline M, Craddock, John A, Liu, Hao, Martinez, Caridad A, Kennedy-Nasser, Alana, Leung, Kathryn S, Gottschalk, Stephen M, Krance, Robert A, Brenner, Malcolm K, Rooney, Cliona M, Heslop, Helen E, Leen, Ann M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831033/
https://ncbi.nlm.nih.gov/pubmed/23783429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.151
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