Controlling Cytomegalovirus: Helping the Immune System Take the Lead

Por Hanley, Patrick J., Bollard, Catherine M.
Publicado em 2014

The time is now: moving toward virus-specific T cells after allogeneic hematopoietic stem cell transplantation as the standard of care

Por Saglio, Francesco, Hanley, Patrick J., Bollard, Catherine M.
Publicado em 2014

Adoptive Immunotherapy using Regulatory T cells and Virus-specific T cells Derived from Cord Blood

Por Hanley, Patrick J., Bollard, Catherine M., Brunstein, Claudio G
Publicado no Cytotherapy (2015)

Expanding Cytotoxic T Lymphocytes from Umbilical Cord Blood that Target Cytomegalovirus, Epstein-Barr Virus, and Adenovirus

Por Hanley, Patrick J., Lam, Sharon, Shpall, Elizabeth J., Bollard, Catherine M.
Publicado em 2012

Improving Clinical Outcomes Using Adoptively Transferred Immune Cells from Umbilical Cord Blood

Por Hanley, Patrick J., Cruz, Conrad Russell, Shpall, Elizabeth J., Bollard, Catherine M.
Publicado em 2010

A single exercise bout enhances the manufacture of viral-specific T-cells from healthy donors: implications for allogeneic adoptive transfer immunotherapy

Por Spielmann, Guillaume, Bollard, Catherine M., Kunz, Hawley, Hanley, Patrick J., Simpson, Richard J.
Publicado no Sci Rep (2016)

A Quantitative Activation Suppression Assay to Evaluate Human Bone Marrow Derived Mesenchymal Stromal Cell Potency

Por Salem, Bahey, Miner, Samantha, Hensel, Nancy F., Battiwalla, Minoo, Keyvanfar, Keyvan, Stroncek, David, Gee, Adrian P., Hanley, Patrick J, Bollard, Catherine M., Ito, Sawa, Barrett, John
Publicado no Cytotherapy (2015)

Manufacturing Mesenchymal Stromal Cells for Phase I Clinical Trials

Por Hanley, Patrick J., Mei, Zhuyong, Cabreira-Hansen, Maria da Graca, Klis, Mariola, Li, Wei, Zhao, Yali, Durett, April G., Zheng, Xingwu, Wang, Yongping, Gee, Adrian P., Horwitz, Edwin M.
Publicado em 2013

Expansion of T cells targeting multiple antigens of cytomegalovirus, Epstein–Barr virus and adenovirus to provide broad antiviral specificity after stem cell transplantation

Por Hanley, Patrick J., Shaffer, Donald R., Cruz, Conrad R. Y., Ku, Stephanie, Tzou, Benjamin, Liu, Hao, Demmler-Harrison, Gail, Heslop, Helen E., Rooney, Clio M., Gottschalk, Stephen, Bollard, Catherine M.
Publicado em 2011

Graft Versus Leukemia Response Without Graft-versus-host Disease Elicited By Adoptively Transferred Multivirus-specific T-cells

Por Melenhorst, Jan J, Castillo, Paul, Hanley, Patrick J, Keller, Michael D, Krance, Robert A, Margolin, Judith, Leen, Ann M, Heslop, Helen E, Barrett, A John, Rooney, Cliona M, Bollard, Catherine M
Publicado no Mol Ther (2015)

Human Parainfluenza Virus-3 can be Targeted by Rapidly ex vivo Expanded T-Lymphocytes

Por McLaughlin, Lauren P., Lang, Haili, Williams, Elizabeth, Wright, Kaylor E., Powell, Allison, Cruz, Conrad R, Colberg-Poley, Anamaris M., Barese, Cecilia, Hanley, Patrick J., Bollard, Catherine M., Keller, Michael D.
Publicado no Cytotherapy (2016)

Low Rate of Infusional Toxicity following Expanded Cord Blood Transplantation

Por Bear, Adham S, Hanley, Patrick J, Bosque, Doyle M, Cruz, Conrad R, Kaur, Indresh, Liu, Hao, Kebriaei, Partow, Hosing, Chitra, Rezvani, Katayoun, Oran, Betul, de Lima, Marcos J, Bollard, Catherine M, Shpall, Elizabeth J
Publicado em 2014

Lovastatin inhibits T cell proliferation while preserving the cytolytic function of EBV-, CMV- and MART-1-specific CTLs

Por Li, Dan, Li, Yufeng, Hernandez, Jessica A., Patenia, Rebecca, Kim, Tae Kon, Khalili, Jahan, Dougherty, Mark C., Hanley, Patrick J., Bollard, Catherine M., Komanduri, Krishna V., Hwu, Patrick, Champlin, Richard E., Radvanyi, Laszlo G., Molldrem, Jeffrey J., Ma, Qing
Publicado no J Immunother (2010)

Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantat...

Por Leen, Ann M., Christin, Anne, Myers, Gary D., Liu, Hao, Cruz, Conrad R., Hanley, Patrick J., Kennedy-Nasser, Alana A., Leung, Kathryn S., Gee, Adrian P., Krance, Robert A., Brenner, Malcolm K., Heslop, Helen E., Rooney, Cliona M., Bollard, Catherine M.
Publicado em 2009

Derivation of human T lymphocytes from cord blood and peripheral blood with antiviral and antileukemic specificity from a single culture as protection against infection and relapse...

Por Micklethwaite, Kenneth P., Savoldo, Barbara, Hanley, Patrick J., Leen, Ann M., Demmler-Harrison, Gail J., Cooper, Laurence J. N., Liu, Hao, Gee, Adrian P., Shpall, Elizabeth J., Rooney, Cliona M., Heslop, Helen E., Brenner, Malcolm K., Bollard, Catherine M., Dotti, Gianpietro
Publicado em 2010

Efficient Manufacturing of Therapeutic Mesenchymal Stromal Cells Using the Quantum Cell Expansion System

Por Hanley, Patrick J., Mei, Zhuyong, Durett, April G., Cabreira-Harrison, Marie da Graca, Klis, Mariola, Li, Wei, Zhao, Yali, Yang, Bing, Parsha, Kaushik, Mir, Osman, Vahidy, Farhaan, Bloom, Debra, Rice, R. Brent, Hematti, Peiman, Savitz, Sean I, Gee, Adrian P.
Publicado em 2014

Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitope...

Por Hanley, Patrick J., Cruz, Conrad Russell Young, Savoldo, Barbara, Leen, Ann M., Stanojevic, Maja, Khalil, Mariam, Decker, William, Molldrem, Jeffrey J., Liu, Hao, Gee, Adrian P., Rooney, Cliona M., Heslop, Helen E., Dotti, Gianpietro, Brenner, Malcolm K., Shpall, Elizabeth J., Bollard, Catherine M.
Publicado em 2009

Adverse Events Following Infusion of T Cells for Adoptive Immunotherapy: A 10 Year Experience

Por Cruz, Conrad Russell, Hanley, Patrick J., Liu, Hao, Torrano, Vicky, Lin, Yu-Feng, Arce, James A., Gottschalk, Stephen, Savoldo, Barbara, Dotti, Gianpietro, Louis, Chrystal U., Leen, Ann M., Gee, Adrian P., Rooney, Cliona M., Brenner, Malcolm K., Bollard, Catherine M., Heslop, Helen E.
Publicado em 2010

CMV-Specific T-cells Generated From Naïve T-cells Recognize Atypical Epitopes And May Be Protective in Vivo

Por Hanley, Patrick J., Melenhorst, Jan J., Nikiforow, Sarah, Scheinberg, Phillip, Blaney, James W., Demmler-Harrison, Gail, Cruz, C. Russell, Lam, Sharon, Krance, Robert A., Leung, Kathryn S., Martinez, Caridad A., Liu, Hao, Heslop, Helen E., Rooney, Cliona M., Shpall, Elizabeth J., Barrett, A. John, Rodgers, John R., Bollard, Catherine M.
Publicado no Sci Transl Med (2015)

Adoptive Immunotherapy for Primary Immunodeficiency Disorders with Virus-Specific T-lymphocytes

Por Naik, Swati, Nicholas, Sarah K, Martinez, Caridad A, Leen, Ann M, Hanley, Patrick J, Gottschalk, Steven M, Rooney, Cliona M, Hanson, I Celine, Krance, Robert A, Cruz, Conrad R, Amrolia, Persis, Lucchini, Giovanna, Bunin, Nancy, Heimall, Jennifer, Klein, Orly R, Gennery, Andrew R, Slatter, Mary A, Vickers, Mark A, Orange, Jordan S, Heslop, Helen E, Bollard, Catherine M, Keller, Michael D
Publicado no J Allergy Clin Immunol (2016)