Adenosine and Bone Metabolism

by Mediero, Aránzazu, Cronstein, Bruce N.
Published 2013

Activation of adenosine A(2A) receptor reduces osteoclast formation via PKA- and ERK1/2-mediated suppression of NFκB nuclear translocation

by Mediero, Aránzazu, Perez-Aso, Miguel, Cronstein, Bruce N
Published 2013

Adenosine A2A receptor (A(2A)R) is a fine-tune regulator of the collagen1:collagen3 balance

by Perez-Aso, Miguel, Mediero, Aránzazu, Cronstein, Bruce N.
Published 2013

Activation of EPAC1/2 is essential for osteoclast formation by modulating NFκB nuclear translocation and actin cytoskeleton rearrangements

by Mediero, Aránzazu, Perez-Aso, Miguel, Cronstein, Bruce N.
Published 2014

Silencing of P2Y(2) receptor delays Ap(4)A-corneal re-epithelialization process

by Crooke, Almudena, Mediero, Aránzazu, Guzmán-Aránguez, Ana, Pintor, Jesús
Published 2009

Adenosine A(2A) receptor (A2AR) stimulation modulates expression of semaphorins 4D and 3A, regulators of bone homeostasis

by Mediero, Aránzazu, Wilder, Tuere, Shah, Lopa, Cronstein, Bruce N.
Published in FASEB J (2018)

Adenosine A(2A) Receptor Ligation Inhibits Osteoclast Formation

by Mediero, Aránzazu, Kara, Firas M., Wilder, Tuere, Cronstein, Bruce N.
Published 2012

Direct or indirect stimulation of adenosine A(2A) receptors enhances bone regeneration as well as bone morphogenetic protein-2

by Mediero, Aránzazu, Wilder, Tuere, Perez-Aso, Miguel, Cronstein, Bruce N.
Published in FASEB J (2015)

Methotrexate prevents wear particle-induced inflammatory osteolysis via activation of the adenosine A(2A) receptor

by Mediero, Aránzazu, Perez-Aso, Miguel, Wilder, Tuere, Cronstein, Bruce N.
Published in Arthritis Rheumatol (2015)

Adenosine A(2A) receptor promotes collagen type III synthesis via β‐catenin activation in human dermal fibroblasts

by Shaikh, Gibran, Zhang, Jin, Perez‐Aso, Miguel, Mediero, Aranzazu, Cronstein, Bruce
Published in Br J Pharmacol (2016)

Adenosine 2A receptor promotes collagen production by human fibroblasts via pathways involving cyclic AMP and AKT but independent of Smad2/3

by Perez-Aso, Miguel, Fernandez, Patricia, Mediero, Aránzazu, Chan, Edwin S., Cronstein, Bruce N.
Published 2014

Netrin-1 and its receptor Unc5b are novel targets for the treatment of inflammatory arthritis

by Mediero, Aránzazu, Wilder, Tuere, Ramkhelawon, Bhama, Moore, Kathryn J., Cronstein, Bruce N.
Published in FASEB J (2016)

Bone Regeneration in Critical Bone Defects Using Three-Dimensionally Printed β-Tricalcium Phosphate/Hydroxyapatite Scaffolds Is Enhanced by Coating Scaffolds with Either Dipyridamo...

by Ishack, Stephanie, Mediero, Aranzazu, Wilder, Tuere, Ricci, John L., Cronstein, Bruce N.
Published in J Biomed Mater Res B Appl Biomater (2015)

Immunolocalisation of P2Y receptors in the rat eye

by Pintor, Jesús, Sánchez-Nogueiro, Jesús, Irazu, Marta, Mediero, Aranzazu, Peláez, Teresa, Peral, Assumpta
Published 2004

Adenosine A2A receptor plays an important role in radiation-induced dermal injury

by Perez-Aso, Miguel, Mediero, Aránzazu, Low, Yee Cheng, Levine, Jamie, Cronstein, Bruce N.
Published in FASEB J (2016)

Netrin-1 Is a Critical Autocrine/Paracrine Factor for Osteoclast Differentiation

by Mediero, Aránzazu, Ramkhelawon, Bhama, Perez-Aso, Miguel, Moore, Kathryn J, Cronstein, Bruce N
Published in J Bone Miner Res (2015)

Adenosine A(2A) Receptor Activation Prevents Wear Particle-Induced Osteolysis

by Mediero, Aránzazu, Frenkel, Sally R., Wilder, Tuere, He, Wenjie, Mazumder, Amitabha, Cronstein, Bruce N.
Published 2012

Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors

by Perez-Aso, Miguel, Montesinos, M. Carmen, Mediero, Aránzazu, Wilder, Tuere, Schafer, Peter H., Cronstein, Bruce
Published in Arthritis Res Ther (2015)

Purinergic System Signaling in Metainflammation-Associated Osteoarthritis

by Gratal, Paula, Lamuedra, Ana, Medina, Juan Pablo, Bermejo-Álvarez, Ismael, Largo, Raquel, Herrero-Beaumont, Gabriel, Mediero, Aránzazu
Published in Front Med (Lausanne) (2020)

A Biodegradable Antifungal-Loaded Sol–Gel Coating for the Prevention and Local Treatment of Yeast Prosthetic-Joint Infections

by Romera, David, Toirac, Beatriz, Aguilera-Correa, John-Jairo, García-Casas, Amaya, Mediero, Aránzazu, Jiménez-Morales, Antonia, Esteban, Jaime
Published in Materials (Basel) (2020)