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Adenosine A(2A) receptor promotes collagen type III synthesis via β‐catenin activation in human dermal fibroblasts
BACKGROUND AND PURPOSE: Adenosine A(2A) receptor stimulation promotes the synthesis of collagen type I and type III (Col1 and Col3), mediators of fibrosis and scarring. The A(2A) receptor modulates collagen balance via cAMP/PKA/p38‐MAPK/Akt pathways. Wnt signalling is important in fibrosis and the c...
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Publicado no: | Br J Pharmacol |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5738670/ https://ncbi.nlm.nih.gov/pubmed/27595240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13615 |
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