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Adenosine A(2A) receptor promotes collagen type III synthesis via β‐catenin activation in human dermal fibroblasts

BACKGROUND AND PURPOSE: Adenosine A(2A) receptor stimulation promotes the synthesis of collagen type I and type III (Col1 and Col3), mediators of fibrosis and scarring. The A(2A) receptor modulates collagen balance via cAMP/PKA/p38‐MAPK/Akt pathways. Wnt signalling is important in fibrosis and the c...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Br J Pharmacol
Päätekijät: Shaikh, Gibran, Zhang, Jin, Perez‐Aso, Miguel, Mediero, Aranzazu, Cronstein, Bruce
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738670/
https://ncbi.nlm.nih.gov/pubmed/27595240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13615
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